Literature DB >> 16888229

PACAP receptor (PAC1-R) expression in rat and rhesus monkey thymus.

N Tokuda1, Y Arudchelvan, T Sawada, Y Adachi, T Fukumoto, M Yasuda, H Sumida, S Shioda, T Fukuda, A Arima, S Kubota.   

Abstract

The expression of PACAP receptor (PAC1-R) was investigated in the thymus of rats and rhesus monkeys. In the rat thymus, PAC1-R positive cells were found in the intermediate type of thymic epithelial cells of the medulla. PAC1-R-positive cells were also seen in the thymic medulla of the rhesus monkey. The thymus showed unusual structures in some rhesus monkey dams (F0) and offspring (F1) exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Additionally, in these rhesus monkeys, PAC1-R expression was different from that in the control thymus.

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Year:  2006        PMID: 16888229     DOI: 10.1196/annals.1317.085

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  2 in total

1.  Dimer-dependent intrinsic/basal activity of the class B G protein-coupled receptor PAC1 promotes cellular anti-apoptotic activity through Wnt/β-catenin pathways that are associated with dimer endocytosis.

Authors:  Rongjie Yu; Zekai Cui; Mei Li; Yanxu Yang; Jiaping Zhong
Journal:  PLoS One       Date:  2014-11-26       Impact factor: 3.240

Review 2.  PACAP38 and PAC1 receptor blockade: a new target for headache?

Authors:  Eloisa Rubio-Beltrán; Edvige Correnti; Marie Deen; Katharina Kamm; Tim Kelderman; Laura Papetti; Simone Vigneri; Antoinette MaassenVanDenBrink; Lars Edvinsson
Journal:  J Headache Pain       Date:  2018-08-07       Impact factor: 7.277

  2 in total

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