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Literature DB >> 168878

Hepatic clearance of adenosine 3:5-cyclic monophosphate from plasma in the rat.

Abstract

Rats were given intravenous injections of cyclic [3H]AMP and the disappearance of radioactivity from plasma and its appearance in bile were followed. Livers were removed and the cyclic [3H]AMP content was measured. The binding of radioactivity to soluble proteins was measured after preparations of a cytoplasmic fraction. Experiments in vitro to determine the ability of hepatic cytoplasmic proteins to bind cyclic [3H]AMP were also carried out. A role for cytoplasmic proteins in the clearance of cyclic AMP from plasma is discounted.

Entities: Chemical Species

Mesh：

Substances：
Proteins
Cyclic AMP

Year: 1975 PMID： 168878 PMCID： PMC1165332 DOI： 10.1042/bj1460509

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

13 in total

1. Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acid.

Authors: O MEULEMANS
Journal: Clin Chim Acta Date: 1960-09 Impact factor: 3.786

2. A new simple method for separation of adenosine 3',5'-cyclic monophosphate from other nucleotides and its use in the assay of adenyl cyclase.

Authors: J Ramachandran
Journal: Anal Biochem Date: 1971-09 Impact factor: 3.365

3. Multiple forms of hepatic adenosine 3':5'-monophosphate dependent protein kinase.

Authors: L J Chen; D A Walsh
Journal: Biochemistry Date: 1971-09-14 Impact factor: 3.162

4. Separation of cyclic 3',5'-nucleoside monophosphates from other nucleotides on aluminum oxide columns. Application to the assay of adenyl cyclase and guanyl cyclase.

Authors: A A White; T V Zenser
Journal: Anal Biochem Date: 1971-06 Impact factor: 3.365

1. Interactions between the effects of alpha- and beta-adrenoceptor agonists and adenine nucleotides on the membrane potential of cells in guinea-pig liver slices.

Authors: D H Jenkinson; K Koller
Journal: Br J Pharmacol Date: 1977-01 Impact factor: 8.739

Review 2. Hormonal effects on the regulation of hepatic heme biosynthesis.

Authors: G S Marks; J K Stephens; P W Fischer; R O Morgan
Journal: Mol Cell Biochem Date: 1979-05-21 Impact factor: 3.396

2 in total

Hepatic clearance of adenosine 3:5-cyclic monophosphate from plasma in the rat.

1. Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acid.

2. A new simple method for separation of adenosine 3',5'-cyclic monophosphate from other nucleotides and its use in the assay of adenyl cyclase.

3. Multiple forms of hepatic adenosine 3':5'-monophosphate dependent protein kinase.

4. Separation of cyclic 3',5'-nucleoside monophosphates from other nucleotides on aluminum oxide columns. Application to the assay of adenyl cyclase and guanyl cyclase.

5. A simple, sensitive method for the assay of adenyl cyclase.

6. Metabolism of cyclic adenosine 3',5'-monophosphate-8-14C by isolated, perfused rat liver.

7. Ligandin: a hepatic protein which binds steroids, bilirubin, carcinogens and a number of exogenous organic anions.

8. Effect of glucagon on net splanchnic cyclic AMP production in normal and diabetic men.

9. Plasma clearance rates and renal clearance of 3H-labeled cyclic AMP and 3H-labeled cyclic GMP in the dog.

10. Effects of parathyroid hormone on plasma and urinary adenosine 3',5'-monophosphate in man.

1. Interactions between the effects of alpha- and beta-adrenoceptor agonists and adenine nucleotides on the membrane potential of cells in guinea-pig liver slices.

Review 2. Hormonal effects on the regulation of hepatic heme biosynthesis.