Literature DB >> 16886985

Pilot study of trigeminal nerve stimulation (TNS) for epilepsy: a proof-of-concept trial.

Christopher M DeGiorgio1, Alan Shewmon, Diane Murray, Todd Whitehurst.   

Abstract

The safety and preliminary efficacy of trigeminal nerve stimulation (TNS) for epilepsy was evaluated in a pilot feasibility study of transcutaneous stimulation of the infraorbital and supraorbital branches of the trigeminal nerve. TNS was well tolerated. Four (57%) of seven subjects who completed >or=3 months experienced a >or=50% reduction in seizure frequency. The results of this pilot study support further investigation into the safety and efficacy of TNS for epilepsy.

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Year:  2006        PMID: 16886985     DOI: 10.1111/j.1528-1167.2006.00594.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  21 in total

1.  Transcutaneous trigeminal nerve stimulation induces a long-term depression-like plasticity of the human blink reflex.

Authors:  Giovanna Pilurzi; Beniamina Mercante; Francesca Ginatempo; Paolo Follesa; Eusebio Tolu; Franca Deriu
Journal:  Exp Brain Res       Date:  2015-10-29       Impact factor: 1.972

2.  Trigeminal nerve stimulation modulates brainstem more than cortical excitability in healthy humans.

Authors:  B Mercante; G Pilurzi; F Ginatempo; A Manca; P Follesa; E Tolu; F Deriu
Journal:  Exp Brain Res       Date:  2015-08-11       Impact factor: 1.972

Review 3.  Restoration of locomotive function in Parkinson's disease by spinal cord stimulation: mechanistic approach.

Authors:  Romulo Fuentes; Per Petersson; Miguel A L Nicolelis
Journal:  Eur J Neurosci       Date:  2010-10       Impact factor: 3.386

4.  Trigeminal nerve stimulation may not be effective for the treatment of refractory partial seizures.

Authors:  Alison M Pack
Journal:  Epilepsy Curr       Date:  2013-07       Impact factor: 7.500

Review 5.  Anatomo-Physiologic Basis for Auricular Stimulation.

Authors:  Beniamina Mercante; Francesca Ginatempo; Andrea Manca; Francesco Melis; Paolo Enrico; Franca Deriu
Journal:  Med Acupunct       Date:  2018-06-01

6.  Effects of acute trigeminal nerve stimulation on rest EEG activity in healthy adults.

Authors:  Francesca Ginatempo; Fabrizio De Carli; Sara Todesco; Beniamina Mercante; Gian Pietro Sechi; Franca Deriu
Journal:  Exp Brain Res       Date:  2018-07-23       Impact factor: 1.972

Review 7.  Electrical stimulation of cranial nerves in cognition and disease.

Authors:  Devin Adair; Dennis Truong; Zeinab Esmaeilpour; Nigel Gebodh; Helen Borges; Libby Ho; J Douglas Bremner; Bashar W Badran; Vitaly Napadow; Vincent P Clark; Marom Bikson
Journal:  Brain Stimul       Date:  2020-02-23       Impact factor: 8.955

8.  Spinal cord stimulation restores locomotion in animal models of Parkinson's disease.

Authors:  Romulo Fuentes; Per Petersson; William B Siesser; Marc G Caron; Miguel A L Nicolelis
Journal:  Science       Date:  2009-03-20       Impact factor: 47.728

Review 9.  Management of the patient with medically refractory epilepsy.

Authors:  Tiziana Granata; Nicola Marchi; Erin Carlton; Chaitali Ghosh; Jorge Gonzalez-Martinez; Andreas V Alexopoulos; Damir Janigro
Journal:  Expert Rev Neurother       Date:  2009-12       Impact factor: 4.618

Review 10.  Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit.

Authors:  Steven C Schachter; John Guttag; Steven J Schiff; Donald L Schomer
Journal:  Epilepsy Behav       Date:  2009-09       Impact factor: 2.937

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