Literature DB >> 1688675

The role of receptor subtype diversity in the CNS.

P R Schofield1, B D Shivers, P H Seeburg.   

Abstract

The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity.

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Year:  1990        PMID： 1688675     DOI： 10.1016/0166-2236(90)90052-c

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  13 in total

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