Literature DB >> 1688593

Murine IL-4 antagonizes the protective effects of IFN on virus-mediated lysis of murine L929 fibroblast cells.

M Lohoff1, E Marsig, M Röllinghoff.   

Abstract

IFN-alpha, -beta, and -gamma protect murine fibroblasts from lysis by vesicular stomatitis virus. In this report we show that culture supernatants derived from a Th cell clone of the TH2-type completely block the protective effects of the IFN. The active component in inhibiting IFN is identified to be IL-4. rIL-4 has similar effects as the T cell supernatant.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 1688593

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  3 in total

1.  Inhibition by interleukin-4 of constitutive beta interferon synthesis in mouse macrophages.

Authors:  P Nickolaus; R Zawatzky
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

2.  mRNA cytokine profile in peripheral blood cells from chronic hepatitis C virus (HCV)-infected patients: effects of interferon-alpha (IFN-alpha) treatment.

Authors:  S Shapiro; V Gershtein; N Elias; E Zuckerman; N Salman; N Lahat
Journal:  Clin Exp Immunol       Date:  1998-10       Impact factor: 4.330

3.  Interferon-gamma and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells.

Authors:  Anna de Lang; Albert D M E Osterhaus; Bart L Haagmans
Journal:  Virology       Date:  2006-07-24       Impact factor: 3.616

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.