| Literature DB >> 16885849 |
C Flagothier1, P Quatresooz, G-E Pierard.
Abstract
INTRODUCTION: The semicircular lipoatrophy of the thighs is a disorder whose incidence remained rare for years. Only recently, an "epidemic" situation emerged, affecting hundreds of subjects who shared a status of administrative employee. OBSERVATION: The older etiopathogenic hypotheses give way to a newer one implying the electromagnetic fields generated by computers and their wirings. The resulting modifications in the intrinsic bioelectrical properties of the skin could influence the biology of macrophages exhibiting lipophagic activity in the hypodermis. The electroactivation of these cells could lead to TNF-alpha release. DISCUSSION: The semicircular lipoatrophy of the thighs is a problem that may affect an employee out of two. Rather than hoping an efficaceous drug therapy, prevention must be advocated by adapting the work conditions related to the use of computerized devices.Entities:
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Year: 2006 PMID: 16885849 DOI: 10.1016/s0151-9638(06)70967-x
Source DB: PubMed Journal: Ann Dermatol Venereol ISSN: 0151-9638 Impact factor: 0.777