Literature DB >> 16884861

Biological cost of fluoroquinolone resistance in Escherichia coli implicated in polyclonal infection.

P Bémer1, S Corvec, C Guitton, C Giraudeau, G Le Gargasson, E Espaze, H Drugeon.   

Abstract

Polyclonal Escherichia coli strains were isolated in a transplanted patient who experienced successive septic shocks. Fluoroquinolone susceptible and resistant strains were corresponding to different PFGE fragment profiles. The gyrA S83L mutation was associated with a reduction in biological fitness. Resistant strain was selected by a long-term single use of ofloxacin.

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Year:  2006        PMID: 16884861     DOI: 10.1016/j.patbio.2006.06.006

Source DB:  PubMed          Journal:  Pathol Biol (Paris)        ISSN: 0369-8114


  2 in total

1.  Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5.

Authors:  W Florian Fricke; Meredith S Wright; Angela H Lindell; Derek M Harkins; Craig Baker-Austin; Jacques Ravel; Ramunas Stepanauskas
Journal:  J Bacteriol       Date:  2008-08-15       Impact factor: 3.490

2.  Plasmidic qnrA3 enhances Escherichia coli fitness in absence of antibiotic exposure.

Authors:  Adrien Michon; Nicolas Allou; Françoise Chau; Isabelle Podglajen; Bruno Fantin; Emmanuelle Cambau
Journal:  PLoS One       Date:  2011-09-07       Impact factor: 3.240

  2 in total

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