Literature DB >> 1688394

Establishment of a new human pancreatic adenocarcinoma cell line, MDAPanc-3.

M L Frazier1, S Pathak, Z W Wang, K Cleary, S E Singletary, M Olive, B Mackay, P A Steck, B Levin.   

Abstract

A new cell line was established from a liver metastasis of a human pancreatic adenocarcinoma. The cell line, MDAPanc-3, which arose from a moderately differentiated adenocarcinoma, produces carbonic anhydrase II mRNA, but no detectable levels of insulin or alpha amylase mRNA. The stem line chromosome number was determined to be 43, with six marker chromosomes. Growth of MDAPanc-3 is stimulated by cholecystokinin (CCK) fragment 26-33. The cell line will be useful in further studies on the mechanism(s) by which CCK stimulates growth of certain human pancreatic adenocarcinomas and normal human pancreatic exocrine tissue.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 1688394     DOI： 10.1097/00006676-199001000-00002

Source DB:  PubMed          Journal:  Pancreas        ISSN： 0885-3177            Impact factor:   3.327


  12 in total

1.  Human cell line from an adenocarcinoma of the ampulla of Vater.

Authors:  M L Frazier; N Brown; S Pathak; B Mackay; K Cleary; M Olive; D R Byrd; D B Evans; B Levin
Journal:  In Vitro Cell Dev Biol       Date:  1992-03

2.  HPAC, a new human glucocorticoid-sensitive pancreatic ductal adenocarcinoma cell line.

Authors:  W R Gower; R M Risch; C V Godellas; P J Fabri
Journal:  In Vitro Cell Dev Biol Anim       Date:  1994-03       Impact factor: 2.416

3.  Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.

Authors:  Liran Zhou; Hongmei Husted; Todd Moore; Mason Lu; Defeng Deng; Yan Liu; Vijaya Ramachandran; Thiruvengadam Arumugam; Christof Niehrs; Huamin Wang; Paul Chiao; Jianhua Ling; Michael A Curran; Anirban Maitra; Mien-Chie Hung; Jeffrey E Lee; Craig D Logsdon; Rosa F Hwang
Journal:  Sci Transl Med       Date:  2018-10-24       Impact factor: 17.956

4.  Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells.

Authors:  Rosa Peracaula; Glòria Tabarés; Anna López-Ferrer; Reinhard Brossmer; Carme de Bolós; Rafael de Llorens
Journal:  Glycoconj J       Date:  2005-03       Impact factor: 2.916

Review 5.  On the role of cholecystokinin in pancreatic cancer.

Authors:  M K Herrington; T E Adrian
Journal:  Int J Pancreatol       Date:  1995-04

6.  Growth inhibition of human pancreatic cancer cells by cholecystokinin receptor antagonist in tissue culture and in nude mice.

Authors:  A Funakoshi; A Kono
Journal:  Gastroenterol Jpn       Date:  1992-02

7.  Presence of CCK-A, B receptors and effect of gastrin and cholecystokinin on growth of pancreatobiliary cancer cell lines.

Authors:  Jin-Young Jang; Sun-Whe Kim; Ja-Lok Ku; Yong-Hyun Park; Jae-Gahb Park
Journal:  World J Gastroenterol       Date:  2005-02-14       Impact factor: 5.742

8.  Profound duodenogastric reflux causes pancreatic growth in rats.

Authors:  T Gasslander; H Mukaida; M K Herrington; R A Hinder; T E Adrian
Journal:  Gut       Date:  1995-01       Impact factor: 23.059

9.  Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma.

Authors:  Qian Liu; Jinyun Chen; Jin Wang; Christopher Amos; Ann M Killary; Subrata Sen; Chongjuan Wei; Marsha L Frazier
Journal:  Mol Carcinog       Date:  2013-05-09       Impact factor: 4.784

10.  Cholecystokinin-A receptor messenger RNA expression in human pancreatic cancer.

Authors:  R Moonka; W Zhou; R H Bell
Journal:  J Gastrointest Surg       Date:  1999 Mar-Apr       Impact factor: 3.267
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.