Literature DB >> 16882716

A genomewide screen for components of the RNAi pathway in Drosophila cultured cells.

Silke Dorner1, Lawrence Lum, Michelle Kim, Renato Paro, Philip A Beachy, Rachel Green.   

Abstract

Posttranscriptional silencing by RNAi is initiated by dsRNAs that are processed into siRNAs that ultimately target homologous mRNAs for degradation. We used luciferase reporter constructs and a cultured cell-based assay to perform a genomewide screen for components of the RNAi pathway in Drosophila melanogaster. The screen identified seven genes that affect the RNAi response, five with previously described function (AGO2, Tis11, Hsc70-3, Hsc70-4, and hdc) and two annotated genes (CG17265 and CG10883).

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Year:  2006        PMID： 16882716      PMCID： PMC1525048          DOI： 10.1073/pnas.0605210103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  64 in total

1.  Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.

Authors:  Jin-Biao Ma; Keqiong Ye; Dinshaw J Patel
Journal:  Nature       Date:  2004-05-20       Impact factor: 49.962

Review 2.  Assembly and function of RNA silencing complexes.

Authors:  Erik J Sontheimer
Journal:  Nat Rev Mol Cell Biol       Date:  2005-02       Impact factor: 94.444

3.  Purified Argonaute2 and an siRNA form recombinant human RISC.

Authors:  Fabiola V Rivas; Niraj H Tolia; Ji-Joon Song; Juan P Aragon; Jidong Liu; Gregory J Hannon; Leemor Joshua-Tor
Journal:  Nat Struct Mol Biol       Date:  2005-03-30       Impact factor: 15.369

Review 4.  miRNAs, cancer, and stem cell division.

Authors:  Carlo M Croce; George A Calin
Journal:  Cell       Date:  2005-07-15       Impact factor: 41.582

5.  Functional genomic analysis of RNA interference in C. elegans.

Authors:  John K Kim; Harrison W Gabel; Ravi S Kamath; Muneesh Tewari; Amy Pasquinelli; Jean-François Rual; Scott Kennedy; Michael Dybbs; Nicolas Bertin; Joshua M Kaplan; Marc Vidal; Gary Ruvkun
Journal:  Science       Date:  2005-03-24       Impact factor: 47.728

6.  Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.

Authors:  Jin-Biao Ma; Yu-Ren Yuan; Gunter Meister; Yi Pei; Thomas Tuschl; Dinshaw J Patel
Journal:  Nature       Date:  2005-03-31       Impact factor: 49.962

7.  Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex.

Authors:  James S Parker; S Mark Roe; David Barford
Journal:  Nature       Date:  2005-03-31       Impact factor: 49.962

8.  Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation.

Authors:  Girish Deshpande; Gretchen Calhoun; Paul Schedl
Journal:  Genes Dev       Date:  2005-07-15       Impact factor: 11.361

9.  Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein.

Authors:  Klaus Förstemann; Yukihide Tomari; Tingting Du; Vasily V Vagin; Ahmet M Denli; Diana P Bratu; Carla Klattenhoff; William E Theurkauf; Phillip D Zamore
Journal:  PLoS Biol       Date:  2005-05-24       Impact factor: 8.029

10.  Principles of microRNA-target recognition.

Authors:  Julius Brennecke; Alexander Stark; Robert B Russell; Stephen M Cohen
Journal:  PLoS Biol       Date:  2005-03       Impact factor: 8.029
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  31 in total

1.  Intronic microRNA precursors that bypass Drosha processing.

Authors:  J Graham Ruby; Calvin H Jan; David P Bartel
Journal:  Nature       Date:  2007-06-24       Impact factor: 49.962

2.  Silencing of genes in cultured Drosophila neurons by RNA interference.

Authors:  Shail K Sharma; Marshall Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-23       Impact factor: 11.205

3.  Proteomics identification of Drosophila small interfering RNA-associated factors.

Authors:  Vincent R Gerbasi; Daniel E Golden; Sara B Hurtado; Erik J Sontheimer
Journal:  Mol Cell Proteomics       Date:  2010-05-15       Impact factor: 5.911

4.  Distinct RNA-dependent RNA polymerases are required for RNAi triggered by double-stranded RNA versus truncated transgenes in Paramecium tetraurelia.

Authors:  Simone Marker; Anne Le Mouël; Eric Meyer; Martin Simon
Journal:  Nucleic Acids Res       Date:  2010-03-03       Impact factor: 16.971

5.  The RNA binding protein Tudor-SN is essential for stress tolerance and stabilizes levels of stress-responsive mRNAs encoding secreted proteins in Arabidopsis.

Authors:  Nicolas Frei dit Frey; Philippe Muller; Fabien Jammes; Dimosthenis Kizis; Jeffrey Leung; Catherine Perrot-Rechenmann; Michele Wolfe Bianchi
Journal:  Plant Cell       Date:  2010-05-18       Impact factor: 11.277

6.  Requirement for CRIF1 in RNA interference and Dicer-2 stability.

Authors:  Su Jun Lim; Anthony Scott; Xiao-Peng Xiong; Shabnam Vahidpour; John Karijolich; Dongdong Guo; Shanshan Pei; Yi-Tao Yu; Rui Zhou; Willis X Li
Journal:  RNA Biol       Date:  2014       Impact factor: 4.652

7.  Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila.

Authors:  Cordula Kemp; Stefanie Mueller; Akira Goto; Vincent Barbier; Simona Paro; François Bonnay; Catherine Dostert; Laurent Troxler; Charles Hetru; Carine Meignin; Sébastien Pfeffer; Jules A Hoffmann; Jean-Luc Imler
Journal:  J Immunol       Date:  2012-12-19       Impact factor: 5.422

8.  Retention and loss of RNA interference pathways in trypanosomatid protozoans.

Authors:  Lon-Fye Lye; Katherine Owens; Huafang Shi; Silvane M F Murta; Ana Carolina Vieira; Salvatore J Turco; Christian Tschudi; Elisabetta Ullu; Stephen M Beverley
Journal:  PLoS Pathog       Date:  2010-10-28       Impact factor: 6.823

Review 9.  Multiple functions of tristetraprolin/TIS11 RNA-binding proteins in the regulation of mRNA biogenesis and degradation.

Authors:  Delphine Ciais; Nadia Cherradi; Jean-Jacques Feige
Journal:  Cell Mol Life Sci       Date:  2012-09-12       Impact factor: 9.261

Review 10.  TIS11 family proteins and their roles in posttranscriptional gene regulation.

Authors:  Maria Baou; Andrew Jewell; John J Murphy
Journal:  J Biomed Biotechnol       Date:  2009-08-06
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