Literature DB >> 16881555

[Eosinophils in nasal polyposis pathogenia. Bibliographic revision].

L Garín Martínez1, M Armengot Carceller, C Carda Batalla.   

Abstract

The aim of this work is to do a review on relations between the eosinophils and nasosinusal polyps. The etiopathogenical action of eosinophils are reviewed, from bone narrow to nasal mucosa infiltration. The mechanism of tissue eosinophilic mediated inflammation, his regulation and the significance of the balance between positive (IL-5) and negative (TGFbeta and IL10) mediators are discussed. We conclude that the degree of eosinophilic infiltration and degranulation's patterns are important aspects conditioning the severity and prognosis of chronic rhinosinusitis and nasosinusal polyps.

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Year:  2006        PMID: 16881555

Source DB:  PubMed          Journal:  An Otorrinolaringol Ibero Am        ISSN: 0303-8874


  1 in total

1.  Human IL-21+IFN-γ+CD4+ T cells in nasal polyps are regulated by IL-12.

Authors:  Li Xiao; Lei Jia; Yannan Zhang; Sifei Yu; Xingmei Wu; Binyan Yang; Huabin Li; Changyou Wu
Journal:  Sci Rep       Date:  2015-08-04       Impact factor: 4.379

  1 in total

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