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Literature DB >> 16879786

The effect of whole organ pancreas transplantation and PIT on diabetic complications.

Timothy C Lee¹, Neal R Barshes, Erin E Agee, Christine A O'Mahoney, F Charles Brunicardi, John A Goss.

Abstract

Diabetes mellitus is a leading cause of morbidity and mortality in the Western world. Currently, the only forms of beta-cell replacement are whole organ pancreas transplantation and pancreatic islet transplantation. Whole organ transplantation has demonstrated benefits in prevention and reversal of diabetic complications with sustainable long-term outcomes. Pancreatic islet transplantation continues to be a field that needs further study to ascertain the true benefit of islet transplantation for diabetic complications. This can only be achieved with improvement in long-term islet allograft survival.

Entities: Disease

Mesh：

Year: 2006 PMID： 16879786 DOI： 10.1007/s11892-006-0068-x

Source DB: PubMed Journal: Curr Diab Rep ISSN： 1534-4827 Impact factor: 4.810

33 in total

1. Immunosuppression and procedure-related complications in 26 patients with type 1 diabetes mellitus receiving allogeneic islet cell transplantation.

Authors: Muhammad M Hafiz; Raquel N Faradji; Tatiana Froud; Antonello Pileggi; David A Baidal; Pablo Cure; Gaston Ponte; Raffaella Poggioli; Agustin Cornejo; Shari Messinger; Camillo Ricordi; Rodolfo Alejandro
Journal: Transplantation Date: 2005-12-27 Impact factor: 4.939

2. Effects of pancreas-kidney transplantation on diabetic retinopathy.

Authors: Rosa Giannarelli; Alberto Coppelli; Mariasole Sartini; Michele Aragona; Ugo Boggi; Fabio Vistoli; Gaetano Rizzo; Stefano Del Prato; Franco Mosca; Piero Marchetti
Journal: Transpl Int Date: 2005-05 Impact factor: 3.782

3. Transplantation of intact pancreatic islets in rats.

Authors: W F Ballinger; P E Lacy
Journal: Surgery Date: 1972-08 Impact factor: 3.982

4. The beneficial effects of pancreas transplant alone on diabetic nephropathy.

Authors: Alberto Coppelli; Rosa Giannarelli; Fabio Vistoli; Stefano Del Prato; Gaetano Rizzo; Franco Mosca; Ugo Boggi; Piero Marchetti
Journal: Diabetes Care Date: 2005-06 Impact factor: 19.112

5. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy.

Authors: John M Lachin; Saul Genuth; Patricia Cleary; Matthew D Davis; David M Nathan
Journal: N Engl J Med Date: 2000-02-10 Impact factor: 91.245

Review 6. Diagnosis and management of diabetic neuropathy.

Authors: Bruce A Perkins; Vera Bril
Journal: Curr Diab Rep Date: 2002-12 Impact factor: 4.810

7. Achievement of insulin independence via pancreatic islet transplantation using a remote isolation center: a first-year review.

Authors: N R Barshes; T Lee; S Goodpasture; F C Brunicardi; R Alejandro; C Ricordi; G Soltes; M Barth; D Hamilton; J A Goss
Journal: Transplant Proc Date: 2004-05 Impact factor: 1.066

8. Development of a human pancreatic islet-transplant program through a collaborative relationship with a remote islet-isolation center.

Authors: John A Goss; Sarah E Goodpastor; F Charles Brunicardi; Merle H Barth; George D Soltes; Alan J Garber; Dale J Hamilton; Rodolfo Alejandro; Camillo Ricordi
Journal: Transplantation Date: 2004-02-15 Impact factor: 4.939

9. Early improvement in cardiac function occurs for pancreas-kidney but not diabetic kidney-alone transplant recipients.

Authors: A O Gaber; S el-Gebely; P Sugathan; D S Elmer; D K Hathaway; R B McCully; M H Shokouh-Amiri; B S Burlew
Journal: Transplantation Date: 1995-04-27 Impact factor: 4.939

10. Changes in liver enzymes after clinical islet transplantation.

Authors: Ehab Rafael; Edmond A Ryan; Breay W Paty; Jose Oberholzer; Sharleen Imes; Peter Senior; Charlotte McDonald; Jonathan R T Lakey; A M James Shapiro
Journal: Transplantation Date: 2003-11-15 Impact factor: 4.939

8 in total

Review 1. Islet transplantation in type 1 diabetes: ongoing challenges, refined procedures, and long-term outcome.

Authors: A M James Shapiro
Journal: Rev Diabet Stud Date: 2012-12-28

2. C-peptide reduces high-glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation in human aortic endothelial cells.

Authors: V Cifarelli; X Geng; A Styche; R Lakomy; M Trucco; P Luppi
Journal: Diabetologia Date: 2011-07-20 Impact factor: 10.122

The effect of whole organ pancreas transplantation and PIT on diabetic complications.

1. Immunosuppression and procedure-related complications in 26 patients with type 1 diabetes mellitus receiving allogeneic islet cell transplantation.

2. Effects of pancreas-kidney transplantation on diabetic retinopathy.

3. Transplantation of intact pancreatic islets in rats.

4. The beneficial effects of pancreas transplant alone on diabetic nephropathy.

5. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy.

Review 6. Diagnosis and management of diabetic neuropathy.

7. Achievement of insulin independence via pancreatic islet transplantation using a remote isolation center: a first-year review.

8. Development of a human pancreatic islet-transplant program through a collaborative relationship with a remote islet-isolation center.

9. Early improvement in cardiac function occurs for pancreas-kidney but not diabetic kidney-alone transplant recipients.

10. Changes in liver enzymes after clinical islet transplantation.

Review 1. Islet transplantation in type 1 diabetes: ongoing challenges, refined procedures, and long-term outcome.

2. C-peptide reduces high-glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation in human aortic endothelial cells.

3. Human C-peptide antagonises high glucose-induced endothelial dysfunction through the nuclear factor-kappaB pathway.

Review 4. Pancreas transplant alone: a procedure coming of age.

Review 5. Proinsulin C-peptide: friend or foe in the development of diabetes-associated complications?

6. Renal and vascular benefits of C-peptide: Molecular mechanisms of C-peptide action.

7. The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells.

Review 8. C-Peptide as a Therapy for Type 1 Diabetes Mellitus.