Literature DB >> 16879362

Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits.

K S Kim1, J J Lee, H Y Shin, B H Choi, C K Lee, J J Kim, B W Cho, T-H Kim.   

Abstract

The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.

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Year:  2006        PMID: 16879362     DOI: 10.1111/j.1365-2052.2006.01482.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  11 in total

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2.  Identify known and novel candidate genes associated with backfat thickness in Duroc pigs by large-scale genome-wide association analysis.

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Journal:  Mar Biotechnol (NY)       Date:  2022-08-09       Impact factor: 3.727

4.  Expression levels of candidate genes for intramuscular fat deposition in two Banna mini-pig inbred lines divergently selected for fatness traits.

Authors:  Su-Mei Zhao; Wei-Zhen Li; Hong-Bin Pan; Ying Huang; Ming-Hua Yang; Hong-Jiang Wei; Shi-Zheng Gao
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Review 7.  Family of melanocortin receptor (MCR) genes in mammals-mutations, polymorphisms and phenotypic effects.

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9.  Detection of quantitative trait loci in Bos indicus and Bos taurus cattle using genome-wide association studies.

Authors:  Sunduimijid Bolormaa; Jennie E Pryce; Kathryn E Kemper; Ben J Hayes; Yuandan Zhang; Bruce Tier; William Barendse; Antonio Reverter; Mike E Goddard
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10.  Multi-breed genome-wide association study reveals novel loci associated with the weight of internal organs.

Authors:  Yuna He; Xinjian Li; Feng Zhang; Ying Su; Lijuan Hou; Hao Chen; Zhiyan Zhang; Lusheng Huang
Journal:  Genet Sel Evol       Date:  2015-11-17       Impact factor: 4.297

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