Literature DB >> 16879104

Mean of CA 125 in making therapy decision in adnexal inflammatory tumors.

Branka Nikolić1, Ana Mitrović, Jelena Lazić.   

Abstract

UNLABELLED: LABORATORY FINDINGS such are white blood count and sedimentation rate are of relative value in inflammations of the upper genital tract and adnexal inflammatory tumors. Antibiotics are administrated in all cases according to the protocol but some of them need operative treatment also. Inflammatory tumors can develop in endometriotic and even in cancer adnexal masses. CA 125 is elevated in great number of patients with advanced ovarian cancer. It can also be elevated in endometriosis, inflammations and in non-gynecological malignancies. Adnexal inflammatory tumor was confirmed in 57 patients. LABORATORY
FINDINGS: white blood count and sedimentation rate were in normal levels in 17 patients. CA 125 was elevated in 27 patients. 49 patients were operated and CA 125 decreased in the first 5 days after the operation. Only 8 patients without CA 125 elevation were successfully treated by mean of antibiotics. Even there is no need for routine examining of serum CA 125 in adnexal inflammatory tumors it can be examined in cases with suspected Doppler ultrasonographic findings or unclear clinical findings. Endometriosis brings some risk of malignancy. Inflammatory tumor can develop in endometriotic tumor as well as in necrotic malignant ovary tissue. These could be reasons for making decision to do the operation in cases with inflammatory tumor followed with increased CA 125, hystological assessment and serious interpretation of final results.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16879104      PMCID: PMC7192643          DOI: 10.17305/bjbms.2006.3160

Source DB:  PubMed          Journal:  Bosn J Basic Med Sci        ISSN: 1512-8601            Impact factor:   3.363


  5 in total

1.  US characterization of ovarian masses: a meta-analysis.

Authors:  K Kinkel; H Hricak; Y Lu; K Tsuda; R A Filly
Journal:  Radiology       Date:  2000-12       Impact factor: 11.105

2.  Screening for familial ovarian cancer: failure of current protocols to detect ovarian cancer at an early stage according to the international Federation of gynecology and obstetrics system.

Authors:  Diane Stirling; D Gareth R Evans; Gabriella Pichert; Andrew Shenton; Elaine N Kirk; Sylvia Rimmer; C Michael Steel; Sheila Lawson; R M Camille Busby-Earle; Jane Walker; Fiona I Lalloo; Diana M Eccles; Anneke M Lucassen; Mary E Porteous
Journal:  J Clin Oncol       Date:  2005-08-20       Impact factor: 44.544

3.  Prognostic importance of preoperative CA-125 in International Federation of Gynecology and Obstetrics stage I epithelial ovarian cancer: an Australian multicenter study.

Authors:  Sellva Paramasivam; Lee Tripcony; Alex Crandon; Micheal Quinn; Ian Hammond; Donald Marsden; Anthony Proietto; Margaret Davy; Jonathan Carter; James Nicklin; Lewis Perrin; Andreas Obermair
Journal:  J Clin Oncol       Date:  2005-08-08       Impact factor: 44.544

4.  Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer.

Authors:  Usha Menon; Steven J Skates; Sara Lewis; Adam N Rosenthal; Barnaby Rufford; Karen Sibley; Nicola Macdonald; Anne Dawnay; Arjun Jeyarajah; Robert C Bast; David Oram; Ian J Jacobs
Journal:  J Clin Oncol       Date:  2005-11-01       Impact factor: 44.544

5.  Compliance of average- and intermediate-risk women to semiannual ovarian cancer screening.

Authors:  Charles W Drescher; Judy Nelson; Sue Peacock; M Robyn Andersen; Martin W McIntosh; Nicole Urban
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2004-04       Impact factor: 4.254

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.