Literature DB >> 1687865

Cellular immunodeficiency in Paget's disease of bone: changes induced by treatment with elcatonin.

A Rapado1, M Yague, M Diaz Curiel, F Ortiz, P Palomino, C de la Piedra, R Torres, B Peramo, E Lopez Gavilanes.   

Abstract

We have found a cellular immune defect (low CD4 T lymphocyte count, high CD8 T lymphocyte count and a low CD4/CD8 ratio) in 39 PDB patients. This finding is not correlated with the bone metabolic activity of the disease. There was an improvement in the cellular immune defect in fifteen patients after treatment with elcatonin. These changes could be related to the improvement in the metabolic derangement or else could be the consequence of an effect on altered immunity.

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Year:  1991        PMID： 1687865     DOI： 10.1007/bf02555857

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  10 in total

1.  Evidence for linkage between HLA and Paget's disease.

Authors:  M Fotino; A Haymovits; C T Falk
Journal:  Transplant Proc       Date:  1977-12       Impact factor: 1.066

2.  Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease.

Authors:  A Kukita; C Chenu; L M McManus; G R Mundy; G D Roodman
Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

3.  Osteocalcin and bone remodelling in Paget's disease of bone, primary hyperparathyroidism, hypercalcaemia of malignancy and involutional osteoporosis.

Authors:  R Torres; C de la Piedra; A Rapado
Journal:  Scand J Clin Lab Invest       Date:  1989-05       Impact factor: 1.713

4.  Risk factors for Paget's disease: a new hypothesis.

Authors:  A M Piga; G López-Abente; A E Ibáñez; A G Vadillo; M G Lanza; V M Jodra
Journal:  Int J Epidemiol       Date:  1988-03       Impact factor: 7.196

5.  Intramuscular administration of salmon calcitonin impairs delayed cutaneous hypersensitivity.

Authors:  S Adami; R Suppi; M Residori; V Braga; M Zamboni; V LoCascio
Journal:  Bone Miner       Date:  1988-04

Review 6.  The epidemiology of Paget's disease of bone.

Authors:  D J Barker
Journal:  Br Med Bull       Date:  1984-10       Impact factor: 4.291

7.  Serum tartrate-resistant acid phosphatase and bone mineral content in postmenopausal osteoporosis.

Authors:  C de la Piedra; R Torres; A Rapado; M Diaz Curiel; N Castro
Journal:  Calcif Tissue Int       Date:  1989-07       Impact factor: 4.333

8.  Immunoglobulin abnormalities in Paget's disease of bone.

Authors:  J N Buxbaum; S Kammerman
Journal:  Clin Exp Immunol       Date:  1984-04       Impact factor: 4.330

9.  Critical evaluation of viral antigen data in Paget's disease of bone.

Authors:  B G Mills; F R Singer
Journal:  Clin Orthop Relat Res       Date:  1987-04       Impact factor: 4.176

10.  Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization.

Authors:  M F Baslé; J G Fournier; S Rozenblatt; A Rebel; M Bouteille
Journal:  J Gen Virol       Date:  1986-05       Impact factor: 3.891
  10 in total
  2 in total

Review 1.  The contribution of Sir James Paget (1814-1894) to the study of rheumatic disease.

Authors:  W Buchanan
Journal:  Clin Rheumatol       Date:  1996-09       Impact factor: 2.980

2.  Regulation of lymphocyte calcitonin receptors by interleukin-1 and interleukin-6.

Authors:  J J Body; G Fernandez; M Lacroix; P Vandenbussche; J Content
Journal:  Calcif Tissue Int       Date:  1994-08       Impact factor: 4.333
  2 in total

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