Literature DB >> 16878065

The rôle of saliva in maintaining oral health and as an aid to diagnosis.

Carmen Llena-Puy1.   

Abstract

Saliva is a complex secretion. 93% by volume is secreted by the major salivary glands and the remaining 7% by the minor glands. 99% of saliva is water and the other 1% is composed of organic and inorganic molecules. While the quantity of saliva is important, so is its quality. The components of saliva, its functions in maintaining oral health and the main factors that cause alterations in salivary secretion will be reviewed, the importance of saliva in caries development and bacterial plaque formation will be discussed and its role as an aid to diagnosing certain pathologies will be examined. Variations in salivary flow can be affected, reversibly or irreversibly, by numerous physiological and pathological factors. Saliva plays an essential role in maintaining the integrity of the oral structures, in personal relationships, in the digestion and in controlling oral infection. The part that saliva plays in protecting teeth from caries can be summarised under four aspects: diluting and eliminating sugars and other substances, buffer capacity, balancing demineralisation/remineralisation and antimicrobial action. Saliva is a promising option for diagnosing certain disorders and monitoring the evolution of certain pathologies or the dosage of medicines or drugs. Its advantages as a diagnostic tool include its being easy to obtain and the positive correlation between many parameters in serum and saliva.

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Year:  2006        PMID: 16878065

Source DB:  PubMed          Journal:  Med Oral Patol Oral Cir Bucal        ISSN: 1698-4447


  51 in total

1.  Salivary phosphate-binding chewing gum reduces hyperphosphatemia in dialysis patients.

Authors:  Vincenzo Savica; Lorenzo A Calò; Paolo Monardo; Paul A Davis; Antonio Granata; Domenico Santoro; Rodolfo Savica; Rosa Musolino; Maria Cristina Comelli; Guido Bellinghieri
Journal:  J Am Soc Nephrol       Date:  2008-11-19       Impact factor: 10.121

2.  The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions.

Authors:  Paul Denny; Fred K Hagen; Markus Hardt; Lujian Liao; Weihong Yan; Martha Arellanno; Sara Bassilian; Gurrinder S Bedi; Pinmannee Boontheung; Daniel Cociorva; Claire M Delahunty; Trish Denny; Jason Dunsmore; Kym F Faull; Joyce Gilligan; Mireya Gonzalez-Begne; Frédéric Halgand; Steven C Hall; Xuemei Han; Bradley Henson; Johannes Hewel; Shen Hu; Sherry Jeffrey; Jiang Jiang; Joseph A Loo; Rachel R Ogorzalek Loo; Daniel Malamud; James E Melvin; Olga Miroshnychenko; Mahvash Navazesh; Richard Niles; Sung Kyu Park; Akraporn Prakobphol; Prasanna Ramachandran; Megan Richert; Sarah Robinson; Melissa Sondej; Puneet Souda; Mark A Sullivan; Jona Takashima; Shawn Than; Jianghua Wang; Julian P Whitelegge; H Ewa Witkowska; Lawrence Wolinsky; Yongming Xie; Tao Xu; Weixia Yu; Jimmy Ytterberg; David T Wong; John R Yates; Susan J Fisher
Journal:  J Proteome Res       Date:  2008-03-25       Impact factor: 4.466

3.  Histamine modulates salivary secretion and diminishes the progression of periodontal disease in rat experimental periodontitis.

Authors:  Juan P Prestifilippo; Eliana Carabajal; Máximo Croci; Javier Fernández-Solari; Elena S Rivera; Juan C Elverdin; Vanina A Medina
Journal:  Inflamm Res       Date:  2012-01-20       Impact factor: 4.575

4.  Salivary glands abnormalities in oculo-auriculo-vertebral spectrum.

Authors:  Davide Brotto; Renzo Manara; Stefania Vio; Sara Ghiselli; Elena Cantone; Rodica Mardari; Irene Toldo; Valentina Stritoni; Alessandro Castiglione; Elisa Lovo; Patrizia Trevisi; Roberto Bovo; Alessandro Martini
Journal:  Clin Oral Investig       Date:  2017-05-22       Impact factor: 3.573

5.  Long-term dexamethasone treatment alters the histomorphology of acinar cells in rat parotid and submandibular glands.

Authors:  Bruna B Bighetti; Gerson F d Assis; Danilo C Vieira; Natalia M Violato; Tania M Cestari; Rumio Taga; José R Bosqueiro; Alex Rafacho
Journal:  Int J Exp Pathol       Date:  2014-09-03       Impact factor: 1.925

Review 6.  The Neonatal Salivary Transcriptome.

Authors:  Jill L Maron
Journal:  Cold Spring Harb Perspect Med       Date:  2015-12-18       Impact factor: 6.915

7.  The Efficacy of a Chewing Gum Containing Phyllanthus emblica Fruit Extract in Improving Oral Health.

Authors:  Qian Gao; Xuemei Li; Haitao Huang; Ying Guan; Qili Mi; Jianhua Yao
Journal:  Curr Microbiol       Date:  2018-03-21       Impact factor: 2.188

8.  Role for Notch signaling in salivary acinar cell growth and differentiation.

Authors:  Howard Dang; Alan L Lin; Binxian Zhang; Hong-Mei Zhang; Michael S Katz; Chih-Ko Yeh
Journal:  Dev Dyn       Date:  2009-03       Impact factor: 3.780

9.  The efficacy of Xialine in patients with Sjögren's syndrome: a single-blind, cross-over study.

Authors:  Esin Alpöz; Pelin Güneri; Gonca Onder; Hülya Cankaya; Yasemin Kabasakal; Timur Köse
Journal:  Clin Oral Investig       Date:  2007-11-14       Impact factor: 3.573

10.  Immunohistochemical localization of Clara cell secretory proteins (CC10-CC26) and Annexin-1 protein in rat major salivary glands.

Authors:  Maria Paola Cecchini; Flavia Merigo; Mirko Cristofoletti; Francesco Osculati; Andrea Sbarbati
Journal:  J Anat       Date:  2009-05       Impact factor: 2.610

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