OBJECTIVE: To describe an infant with severe pertussis successfully treated with leukopheresis. DESIGN: Case report. SETTING: Pediatric intensive care unit of a children's hospital. PATIENT: Five-wk-old female with pertussis complicated by cardiorespiratory failure. INTERVENTIONS: Single leukopheresis treatment. MEASUREMENTS AND MAIN RESULTS: Normalization of the white blood cell count and marked cardiorespiratory improvement after treatment; patient survived. CONCLUSION: Given the temporal association between treatment and improvement, we hypothesize that the markedly elevated white blood cell count has a major role in the cardiopulmonary compromise.
OBJECTIVE: To describe an infant with severe pertussis successfully treated with leukopheresis. DESIGN: Case report. SETTING: Pediatric intensive care unit of a children's hospital. PATIENT: Five-wk-old female with pertussis complicated by cardiorespiratory failure. INTERVENTIONS: Single leukopheresis treatment. MEASUREMENTS AND MAIN RESULTS: Normalization of the white blood cell count and marked cardiorespiratory improvement after treatment; patient survived. CONCLUSION: Given the temporal association between treatment and improvement, we hypothesize that the markedly elevated white blood cell count has a major role in the cardiopulmonary compromise.
Authors: Guillaume Maitre; Damien Schaffner; Julia Natterer; David Longchamp; Thomas Ferry; Manuel Diezi; Stefano Di Bernardo; Marie-Hélène Perez; Vivianne Amiet Journal: Front Pediatr Date: 2018-09-26 Impact factor: 3.418