Literature DB >> 16878036

Hospital volume and mortality for mechanical ventilation of medical and surgical patients: a population-based analysis using administrative data.

Dale M Needham1, Susan E Bronskill, Deanna M Rothwell, William J Sibbald, Peter J Pronovost, Andreas Laupacis, Thérèse A Stukel.   

Abstract

OBJECTIVE: In an effort to improve efficiency and quality of care, regionalization of adult critical care services, similar to trauma and neonatal intensive care, has been suggested. However, there is little research to understand if hospitals with higher patient volumes have better outcomes. Our objective is to determine whether hospital volume is associated with improved survival for medical or surgical patients receiving mechanical ventilation.
DESIGN: Population-based retrospective cohort study.
SETTING: Province of Ontario, Canada. PATIENTS: A total of 13,846 medical and 6,373 surgical patients receiving mechanical ventilation for greater than two consecutive days between 1998 and 2000.
INTERVENTIONS: None. MEASUREMENTS: Odds ratio for death within 30 days of initiation of mechanical ventilation was calculated in relation to hospital volume of ventilation. Estimates were adjusted for patient demographics, diagnoses, and urgency status; hospital region and rural location; and accounted for clustering within hospitals. MAIN
RESULTS: There was no effect of volume on mortality for surgical patients. After adjustment for clustering, among medical patients, the lowest-volume category (<100 episodes/yr) had a nonsignificant increase in mortality, with an odds ratio (95% confidence interval) of 1.13 (0.87-1.47) compared with the highest-volume category (> or =700 episodes/yr). A post hoc analysis revealed that within the lowest-volume category, the proportion of patients transferred to larger hospitals was 81% for hospitals with <20 episodes/yr and only 32% for hospitals with 20-99 episodes/yr, with odds ratios (95% confidence interval) for mortality of 0.74 (0.49-1.12) and 1.18 (0.90-1.54), respectively, compared with the highest-volume category.
CONCLUSIONS: For surgical patients requiring mechanical ventilation for >2 days, hospital volume had no effect on mortality. For medical patients, higher mortality may occur in a subgroup of low-volume hospitals that do not routinely transfer their patients to larger-volume facilities. This finding needs further investigation in a larger-sized study.

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Year:  2006        PMID: 16878036     DOI: 10.1097/01.CCM.0000233858.85802.5C

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  25 in total

1.  [Volume theory--volume void?!].

Authors:  Jürgen Graf; Uwe Janssens
Journal:  Wien Klin Wochenschr       Date:  2009       Impact factor: 1.704

2.  Patient and Hospital Characteristics Associated with Interhospital Transfer for Adults with Ventilator-Dependent Respiratory Failure.

Authors:  Nandita R Nadig; Andrew J Goodwin; Annie N Simpson; Kit N Simpson; Jeremy Richards; Dee W Ford
Journal:  Ann Am Thorac Soc       Date:  2017-05

3.  Case Volume-Outcomes Associations Among Patients With Severe Sepsis Who Underwent Interhospital Transfer.

Authors:  Uchenna R Ofoma; John Dahdah; Shravan Kethireddy; Daniel Maeng; Allan J Walkey
Journal:  Crit Care Med       Date:  2017-04       Impact factor: 7.598

Review 4.  The Volume-Outcome Relationship in Critical Care: A Systematic Review and Meta-analysis.

Authors:  Yên-Lan Nguyen; David J Wallace; Youri Yordanov; Ludovic Trinquart; Josefin Blomkvist; Derek C Angus; Jeremy M Kahn; Philippe Ravaud; Bertrand Guidet
Journal:  Chest       Date:  2015-07       Impact factor: 9.410

Review 5.  Does patient volume affect clinical outcomes in adult intensive care units?

Authors:  Mrudula H Kanhere; Harsh A Kanhere; Alun Cameron; Guy J Maddern
Journal:  Intensive Care Med       Date:  2012-04-05       Impact factor: 17.440

6.  Should mechanical ventilation care be centralized and should we thus transfer all ventilated patients to high volume units? Take a breath first.

Authors:  Marcus J Schultz; Peter E Spronk
Journal:  Intensive Care Med       Date:  2014-02-07       Impact factor: 17.440

7.  Is the volume of mechanically ventilated admissions to UK critical care units associated with improved outcomes?

Authors:  Jason Shahin; D A Harrison; K M Rowan
Journal:  Intensive Care Med       Date:  2014-02-07       Impact factor: 17.440

8.  Hospital Mechanical Ventilation Volume and Patient Outcomes: Too Much of a Good Thing?

Authors:  Anuj B Mehta; Allan J Walkey; Douglas Curran-Everett; Daniel Matlock; Ivor S Douglas
Journal:  Crit Care Med       Date:  2019-03       Impact factor: 7.598

9.  Uncharted paths: hospital networks in critical care.

Authors:  Theodore J Iwashyna; Jason D Christie; Jeremy M Kahn; David A Asch
Journal:  Chest       Date:  2009-03       Impact factor: 9.410

Review 10.  Pro/con debate: do the benefits of regionalized critical care delivery outweigh the risks of interfacility patient transport?

Authors:  Jeffrey M Singh; Russell D MacDonald
Journal:  Crit Care       Date:  2009-08-10       Impact factor: 9.097

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