| Literature DB >> 16877809 |
Maria Constantinou1, Aleksandra Binka-Kowalska, Edyta Borkowska, Ewa Zajac, Paweł Jałmuzna, Józef Matych, Agnieszka Nawrocka, Bogdan Kałuzewski.
Abstract
Multiplex FISH (UroVysion), Comparative Genomic Hybridization (CGH), and Multitemperature Single-Strand Conformation Polymorphism (MSSCP) were applied for non-invasive diagnosis and prognosis of bladder cancer. The UroVysion test was positive in 80% of patients with pT1 and in 100% of patients with either pT2 or pT3 tumours. Tumours with pT3T4 stages were characterized by high numbers of chromosomal imbalances, detected by CGH. The mutation of the p53 gene was detected in 16% of patients, but only in those with pT2 or pT3 tumours.Entities:
Mesh：
Year: 2006 PMID： 16877809 DOI： 10.1007/BF03194636
Source DB: PubMed Journal: J Appl Genet ISSN： 1234-1983 Impact factor: 3.240