Literature DB >> 1687651

Transcriptional regulation of liver-specific gene expression.

V De Simone1, R Cortese.   

Abstract

Liver-specific gene expression is regulated by four families of transcriptional activatory proteins that are not liver-specific, but are still restricted to a subset of tissues. The current opinion is that liver-specificity is a consequence of the combinatorial action of these factors, which could represent 'functional compartments' coexisting in the hepatocyte.

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Year:  1991        PMID: 1687651     DOI: 10.1016/0955-0674(91)90114-e

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  23 in total

1.  Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.

Authors:  D Chaya; C Fougère-Deschatrette; M C Weiss
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

2.  TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation.

Authors:  M Zannini; V Avantaggiato; E Biffali; M I Arnone; K Sato; M Pischetola; B A Taylor; S J Phillips; A Simeone; R Di Lauro
Journal:  EMBO J       Date:  1997-06-02       Impact factor: 11.598

3.  Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX).

Authors:  M K Ray; C Y Chen; R J Schwartz; F J DeMayo
Journal:  Mol Cell Biol       Date:  1996-05       Impact factor: 4.272

4.  Expression liver-directed genes by employing synthetic transcriptional control units.

Authors:  Marie-Luise Lemken; Wolfgang-A Wybranietz; Ulrike Schmidt; Florian Graepler; Sorin Armeanu; Michael Bitzer; Ulrich-M Lauer
Journal:  World J Gastroenterol       Date:  2005-09-14       Impact factor: 5.742

5.  Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factors.

Authors:  A Rollier; C M DiPersio; S Cereghini; K Stevens; F Tronche; K Zaret; M C Weiss
Journal:  Mol Biol Cell       Date:  1993-01       Impact factor: 4.138

6.  Individual mouse alpha-fetoprotein enhancer elements exhibit different patterns of tissue-specific and hepatic position-dependent activities.

Authors:  T M Ramesh; A W Ellis; B T Spear
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272

7.  Functional synergism in the carbohydrate-induced activation of liver-type pyruvate kinase gene expression.

Authors:  Z Liu; H C Towle
Journal:  Biochem J       Date:  1995-05-15       Impact factor: 3.857

8.  The distal enhancer implicated in the developmental regulation of the tyrosine aminotransferase gene is bound by liver-specific and ubiquitous factors.

Authors:  D Nitsch; G Schütz
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

9.  Structure of the gene encoding hepatocyte nuclear factor 1 (HNF1).

Authors:  I Bach; M Pontoglio; M Yaniv
Journal:  Nucleic Acids Res       Date:  1992-08-25       Impact factor: 16.971

10.  CCAAT/enhancer binding protein regulates the promoter activity of the rat GLUT2 glucose transporter gene in liver cells.

Authors:  J W Kim; Y H Ahn
Journal:  Biochem J       Date:  1998-11-15       Impact factor: 3.857

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