Literature DB >> 1687649

The role of heat-shock proteins as molecular chaperones.

W J Welch1.   

Abstract

Recent studies have revealed that protein folding and assembly events in vivo require the participation of accessory components, now being referred to as 'molecular chaperones'. A number of chaperones have been identified as members of the heat-shock (or stress) protein family. This review discusses the roles of two classes of chaperones, the heat-shock protein 70 and groEL/ES families, in facilitating protein maturation, and describes how such events are perturbed in the cell subjected to metabolic stress.

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Year:  1991        PMID： 1687649     DOI： 10.1016/0955-0674(91)90125-i

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  36 in total

1.  Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells.

Authors:  Kai Yang; Hexin Shi; Rong Qi; Shaogang Sun; Yujie Tang; Bianhong Zhang; Chen Wang
Journal:  Mol Biol Cell       Date:  2006-01-04       Impact factor: 4.138

2.  Involvement of molecular chaperones and the transcription factor Nrf2 in neuroprotection mediated by para-substituted-4,5-diaryl-3-thiomethyl-1,2,4-triazines.

Authors:  Fariba Khodagholi; Niloufar Ansari; Mohsen Amini; Solaleh Khoramian Tusi
Journal:  Cell Stress Chaperones       Date:  2012-01-04       Impact factor: 3.667

3.  A portion of RNA polymerase II molecules has a component essential for stress responses and stress survival.

Authors:  M Choder; R A Young
Journal:  Mol Cell Biol       Date:  1993-11       Impact factor: 4.272

4.  Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

Authors:  Gnana Prakasam Krishnamoorthy; Teresa Guida; Luigi Alfano; Elvira Avilla; Massimo Santoro; Francesca Carlomagno; Rosa Marina Melillo
Journal:  J Biol Chem       Date:  2013-04-29       Impact factor: 5.157

Review 5.  New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.

Authors:  Yanyan Li; Tao Zhang; Steven J Schwartz; Duxin Sun
Journal:  Drug Resist Updat       Date:  2009 Feb-Apr       Impact factor: 18.500

6.  IIp45 inhibits cell migration through inhibition of HDAC6.

Authors:  Ying Wu; Sonya W Song; Jiyuan Sun; Janet M Bruner; Gregory N Fuller; Wei Zhang
Journal:  J Biol Chem       Date:  2009-12-12       Impact factor: 5.157

Review 7.  Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.

Authors:  Alison Donnelly; Brian S J Blagg
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

8.  Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

Authors:  Jung Jin Kim; Laura Mandelli; Suzy Lim; Hyun Kook Lim; Oh Joo Kwon; Chi Un Pae; Alessandro Serretti; Vishwajit L Nimgaonkar; In-Ho Paik; Tae-Youn Jun
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-06       Impact factor: 5.270

9.  The intracellular Ca(2+)-pump inhibitors thapsigargin and cyclopiazonic acid induce stress proteins in mammalian chondrocytes.

Authors:  T C Cheng; H P Benton
Journal:  Biochem J       Date:  1994-07-15       Impact factor: 3.857

10.  Chlamydomonas transcripts encoding three divergent plastid chaperonins are heat-inducible.

Authors:  M D Thompson; C D Paavola; T R Lenvik; J S Gantt
Journal:  Plant Mol Biol       Date:  1995-03       Impact factor: 4.076
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