Literature DB >> 16876408

Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue.

Naoshi Kojima1, Maiko Sugino, Akiko Mikami, Ken Nonaka, Yumi Fujinawa, Isamu Muto, Kenichi Matsubara, Eiko Ohtsuka, Yasuo Komatsu.   

Abstract

We developed novel amino-modifying reagents, of which an amino group was connected with an aromatic residue by aliphatic linker. It was proved that the insertion of the aromatic residue could increase the reactivity of the amino group on oligonucleotides in comparison with conventional amino-modification.

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Year:  2006        PMID: 16876408     DOI: 10.1016/j.bmcl.2006.07.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Nanomaterial-assisted signal enhancement of hybridization for DNA biosensors: a review.

Authors:  Jinhuai Liu; Jinyun Liu; Liangbao Yang; Xing Chen; Meiyun Zhang; Fanli Meng; Tao Luo; Minqiang Li
Journal:  Sensors (Basel)       Date:  2009-09-11       Impact factor: 3.576

2.  Analysis of GTP addition in the reverse (3'-5') direction by human tRNAHis guanylyltransferase.

Authors:  Akiyoshi Nakamura; Daole Wang; Yasuo Komatsu
Journal:  RNA       Date:  2021-03-23       Impact factor: 5.636

3.  The products from fermentation of wheat bran fiber by Auricularia polytricha strain and the effects of the products on rheological properties of dough sheet.

Authors:  Shiyu Jiang; Li Li; Limin Li; Xueling Zheng; Zhengzhe Li; Xin Song
Journal:  Food Sci Nutr       Date:  2020-02-06       Impact factor: 2.863

  3 in total

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