| Literature DB >> 16876211 |
Rémy Bertrand Teponno1, Azefack Léon Tapondjou, Donatien Gatsing, Jules Désiré Djoukeng, Eliane Abou-Mansour, Raphael Tabacchi, Pierre Tane, H Stoekli-Evans, David Lontsi.
Abstract
Two clerodane diterpenoids, Bafoudiosbulbins A 1, and B 2, together with five known compounds: tetracosanoic acid, 1-(tetracosanoyl)-glycerol, trans-tetracosanylferulate, beta-sitosterol and 3-O-beta-D-glucopyranosyl-beta-sitosterol were isolated from the tubers of Dioscorea bulbifera L. var sativa. Their structures were established by spectroscopic methods (1D and 2D-NMR, MS) and X-ray crystallographic diffraction analysis of compound 1. The CH2Cl2-soluble portion of the crude extract and the two clerodanes were screened for anti-bacterial activity using both agar diffusion and broth dilution techniques against Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Salmonella typhi, Salmonella paratyphi A and Salmonella paratyphi B. They both showed significant activities against P. aeruginosa, S. typhi, S. paratyphi A and S. paratyphi B.Entities:
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Year: 2006 PMID： 16876211 DOI： 10.1016/j.phytochem.2006.06.019
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072