OBJECTIVE: To present a series of 13 different cases of oral lichen planus (OLP) in 6 different families. STUDY DESIGN: From 249 lichen planus cases, we found 13 that could be considered to be family related. A study of these 13 cases of OLP was carried out across the various generations, and the means of presentation, placement, and injuries were studied, as well as signs and symptoms. RESULTS: The predominant affectation was in the women; only 2 patients were male. The mothers showed predominance toward erythematous OLP with greater symptoms, and in their children, symptom-free white OLP was predominant. CONCLUSIONS: It seems there may be some genetic predisposition toward OLP.
OBJECTIVE: To present a series of 13 different cases of oral lichen planus (OLP) in 6 different families. STUDY DESIGN: From 249 lichen planus cases, we found 13 that could be considered to be family related. A study of these 13 cases of OLP was carried out across the various generations, and the means of presentation, placement, and injuries were studied, as well as signs and symptoms. RESULTS: The predominant affectation was in the women; only 2 patients were male. The mothers showed predominance toward erythematous OLP with greater symptoms, and in their children, symptom-free white OLP was predominant. CONCLUSIONS: It seems there may be some genetic predisposition toward OLP.
Authors: Majid Moshirfar; Harry Y Liu; David B Rosen; Madeline B Heiland; Masoud Mirghorbani; Yasmyne C Ronquillo; Phillip C Hoopes Journal: Med Hypothesis Discov Innov Ophthalmol Date: 2019
Authors: Zeinab Abd El-Samad Ibrahim; Amal Ahmad El-Ashmawy; Yomna Mazid El-Hamd Neinaa; Dareen Abd El-Aziz Mohammad Journal: Indian J Dermatol Date: 2019 Jul-Aug Impact factor: 1.494