Literature DB >> 1687487

A role for CD8+ T lymphocytes in the pathogenesis of AIDS.

A Aranda-Anzaldo1.   

Abstract

Experimental and clinical evidence is presented which supports the hypothesis that CD8+ T lymphocytes aimed at suppressing HIV replication in infected CD4+ T cells may have an important role in the pathogenesis of AIDS by directly causing a decrease in CD4+ T lymphocyte numbers. Possible models to test this hypothesis are discussed.

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Year:  1991        PMID： 1687487      PMCID： PMC7135057          DOI： 10.1016/0923-2494(91)90099-5

Source DB:  PubMed          Journal:  Res Immunol        ISSN： 0923-2494


  61 in total

Review 1.  Does HIV cause AIDS? An historical perspective.

Authors:  A S Evans
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1989

2.  Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations.

Authors:  A Meyerhans; R Cheynier; J Albert; M Seth; S Kwok; J Sninsky; L Morfeldt-Månson; B Asjö; S Wain-Hobson
Journal:  Cell       Date:  1989-09-08       Impact factor: 41.582

3.  Do tolerant T cells exist?

Authors:  D L Mueller
Journal:  Nature       Date:  1989-06-15       Impact factor: 49.962

4.  Human immunodeficiency virus type 1 infection in homosexual men who remain seronegative for prolonged periods.

Authors:  D T Imagawa; M H Lee; S M Wolinsky; K Sano; F Morales; S Kwok; J J Sninsky; P G Nishanian; J Giorgi; J L Fahey
Journal:  N Engl J Med       Date:  1989-06-01       Impact factor: 91.245

Review 5.  The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

Authors:  A S Fauci
Journal:  Science       Date:  1988-02-05       Impact factor: 47.728

Review 6.  The immunopharmacology of cyclophosphamide.

Authors:  F L Shand
Journal:  Int J Immunopharmacol       Date:  1979

7.  Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection.

Authors:  J E Brinchmann; J Albert; F Vartdal
Journal:  J Virol       Date:  1991-04       Impact factor: 5.103

8.  Heterophil-negative mononucleosis-like illnesses with atypical lymphocytosis in patients undergoing seroconversions to the human immunodeficiency virus.

Authors:  T A Steeper; C A Horwitz; M Hanson; W Henle; G Henle; H Rosenstein; L Peterson; T W Amsden; M Belzer
Journal:  Am J Clin Pathol       Date:  1988-08       Impact factor: 2.493

9.  CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication.

Authors:  C M Walker; D J Moody; D P Stites; J A Levy
Journal:  Science       Date:  1986-12-19       Impact factor: 47.728

10.  In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6).

Authors:  P Lusso; P D Markham; E Tschachler; F di Marzo Veronese; S Z Salahuddin; D V Ablashi; S Pahwa; K Krohn; R C Gallo
Journal:  J Exp Med       Date:  1988-05-01       Impact factor: 14.307
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  4 in total

1.  Quantitative MRI Measures in SIV-Infected Macaque Brains.

Authors:  Xiaodong Zhang; Chunxia Li
Journal:  J Clin Cell Immunol       Date:  2013

2.  A longitudinal magnetization transfer imaging evaluation of brain injury in a macaque model of neuroAIDS.

Authors:  Chun-Xia Li; James G Herndon; Francis J Novembre; Xiaodong Zhang
Journal:  AIDS Res Hum Retroviruses       Date:  2014-11-06       Impact factor: 2.205

3.  Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group.

Authors:  A L Landay; D Brambilla; J Pitt; G Hillyer; D Golenbock; J Moye; S Landesman; J Kagan
Journal:  Clin Diagn Lab Immunol       Date:  1995-07

4.  2-Carboxyethylgermanium sesquioxide, a synthetic organogermanium compound, as an inducer of contrasuppressor T cells.

Authors:  K Ikemoto; M Kobayashi; T Fukumoto; M Morimatsu; R B Pollard; F Suzuki
Journal:  Experientia       Date:  1996-02-15
  4 in total

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