Literature DB >> 16872821

The impact of long-term conventional treatment for overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease) on concurrent erectile dysfunction.

Petros Perimenis1, Kyriakos Karkoulias, Agelis Konstantinopoulos, Manos Alchanatis, Paraskevi P Perimeni, Anastasios Athanasopoulos, Konstantinos Spyropoulos.   

Abstract

PURPOSE: To assess the improvement of concurrent erectile dysfunction (ED) in men with overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease), treated with continuous positive airway pressure (CPAP) and bronchodilators.
MATERIAL AND METHODS: We evaluated 48 men of a mean age of 52.8+/-10 years suffering from both obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), and concurrent ED. They were treated with conventional for pulmonary obstruction therapy (CPAP and bronchodilators) for 6 months and then their erectile function (EF) status was reassessed. ED was considered as improved, if ED intensity score increased for at least five points compared to that of baseline. The determinants for improvement of ED were also evaluated, as well as patient's personal degree of satisfaction with the treatment they received as far as the disorder was concerned.
RESULTS: EF was improved in 12 patients (25%), but only two thirds of them were satisfied with the grade of improvement after treatment. ED improvement was related positively with age and apnea/hypopnea index and negatively with ED duration. ED intensity score, O(2) saturation at night and BMI were not significantly related to the outcome of EF improvement.
CONCLUSIONS: Conventional treatment for OSA and COPD, has a positive effect on concurrent ED on the minority of patients. This effect is possibly due to the improvement of respiration during sleep with CPAP and of oxygenation with bronchodilators continuously. Of the improved men, one third was not satisfied with the impact of this treatment modality on their EF. It is likely that specific for ED treatment is needed in these individuals.

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Year:  2006        PMID: 16872821     DOI: 10.1016/j.rmed.2006.06.012

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  5 in total

1.  Effects of nasal continuous positive airway pressure therapy on partners' sexual lives.

Authors:  Mustafa Acar; Coskun Kaya; Tolgahan Catli; Deniz Hancı; Ozge Bolluk; Yunus Aydin
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-02-10       Impact factor: 2.503

Review 2.  Sleep-disordered breathing and COPD: the overlap syndrome.

Authors:  Robert L Owens; Atul Malhotra
Journal:  Respir Care       Date:  2010-10       Impact factor: 2.258

Review 3.  A Clinical Perspective of Sleep and Andrological Health: Assessment, Treatment Considerations, and Future Research.

Authors:  Peter Y Liu
Journal:  J Clin Endocrinol Metab       Date:  2019-10-01       Impact factor: 5.958

Review 4.  Review of the prevalence, pathogenesis and management of OSA-COPD overlap.

Authors:  M Brennan; M J McDonnell; S M Walsh; F Gargoum; R Rutherford
Journal:  Sleep Breath       Date:  2022-01-16       Impact factor: 2.816

Review 5.  Effects of obstructive sleep apnea and its treatment over the erectile function: a systematic review.

Authors:  Felix Campos-Juanatey; Marcos Fernandez-Barriales; Monica Gonzalez; Jose A Portillo-Martin
Journal:  Asian J Androl       Date:  2017 May-Jun       Impact factor: 3.285

  5 in total

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