| Literature DB >> 16872227 |
Ching-Yao Chang1, Hui-Ming Liu, Tahsin J Chow.
Abstract
The first total synthesis of louisianin A, 4-allyl-6,7-dihydro-1-hydroxycyclopenta[c]pyridin-5-one, is achieved from 2-chloro-4-cyanopyridine 5 via seven steps in an overall 24% yield. The key step is a cyclization-decarboxylation sequence toward the formation of a cyclopentenone ring.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16872227 DOI： 10.1021/jo060935j
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354