The epidemiologic scope of Kaposi's sarcoma.

The unique epidemiology of Kaposi's sarcoma among patients with the acquired immunodeficiency syndrome suggests a multifactorial cause. Although the human immunodeficiency virus (HIV) plays a major role in the pathogenesis of this condition, it is not the sole cause. Other factors, such as a second sexually transmitted organism, genetics, and nitrite inhalant use, may predispose HIV-infected persons to Kaposi's sarcoma.