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Literature DB >> 16871206

Future lab-on-a-chip technologies for interrogating individual molecules.

Abstract

Advances in technology have allowed chemical sampling with high spatial resolution and the manipulation and measurement of individual molecules. Adaptation of these approaches to lab-on-a-chip formats is providing a new class of research tools for the investigation of biochemistry and life processes.

Mesh：

Year: 2006 PMID： 16871206 DOI： 10.1038/nature05061

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

95 in total

1. Surface charge, electroosmotic flow and DNA extension in chemically modified thermoplastic nanoslits and nanochannels.

Authors: Franklin I Uba; Swathi R Pullagurla; Nichanun Sirasunthorn; Jiahao Wu; Sunggook Park; Rattikan Chantiwas; Yoon-Kyoung Cho; Heungjoo Shin; Steven A Soper
Journal: Analyst Date: 2015-01-07 Impact factor: 4.616

Review 2. Nanobiochips.

Authors: Ramūnas Valiokas
Journal: Cell Mol Life Sci Date: 2011-11-01 Impact factor: 9.261

3. Resonances arising from hydrodynamic memory in Brownian motion.

Authors: Thomas Franosch; Matthias Grimm; Maxim Belushkin; Flavio M Mor; Giuseppe Foffi; László Forró; Sylvia Jeney
Journal: Nature Date: 2011-10-05 Impact factor: 49.962

4. Dynamic in situ chromosome immobilisation and DNA extraction using localized poly(N-isopropylacrylamide) phase transition.

Authors: Johan Eriksen; Anil Haraksingh Thilsted; Rodolphe Marie; Christopher James Lüscher; Lars Bue Nielsen; Winnie Edith Svendsen; Peter Szabo; Anders Kristensen
Journal: Biomicrofluidics Date: 2011-09-20 Impact factor: 2.800

Future lab-on-a-chip technologies for interrogating individual molecules.

1. Surface charge, electroosmotic flow and DNA extension in chemically modified thermoplastic nanoslits and nanochannels.

Review 2. Nanobiochips.

3. Resonances arising from hydrodynamic memory in Brownian motion.

4. Dynamic in situ chromosome immobilisation and DNA extraction using localized poly(N-isopropylacrylamide) phase transition.

5. Simulation of conformational preconditioning strategies for electrophoretic stretching of DNA in a microcontraction.

6. Automated microfluidic protein immunoblotting.

7. Single-molecule denaturation mapping of DNA in nanofluidic channels.

8. Optofluidic wavelength division multiplexing for single-virus detection.

Review 9. Micro- and nanoscale devices for the investigation of epigenetics and chromatin dynamics.

10. Loss-based optical trap for on-chip particle analysis.