Literature DB >> 16870800

Is stavudine triphosphate a natural metabolite of zidovudine?

Henri Benech, François Becher, Alain Pruvost, Jacques J Grassi.   

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Year:  2006        PMID： 16870800      PMCID： PMC1538651          DOI： 10.1128/AAC.00412-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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  16 in total

1.  A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.

Authors:  François Becher; Alain Pruvost; Jane Gale; Philippe Couerbe; Cécile Goujard; Valerie Boutet; Eric Ezan; Jacques Grassi; Henri Benech
Journal:  J Mass Spectrom       Date:  2003-08       Impact factor: 1.982

2.  Determination of zidovudine triphosphate intracellular concentrations in peripheral blood mononuclear cells from human immunodeficiency virus-infected individuals by tandem mass spectrometry.

Authors:  E Font; O Rosario; J Santana; H García; J P Sommadossi; J F Rodriguez
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

3.  Simultaneous determination of Ziagen and its phosphorylated metabolites by ion-pairing high-performance liquid chromatography-tandem mass spectrometry.

Authors:  E N Fung; Z Cai; T C Burnette; A K Sinhababu
Journal:  J Chromatogr B Biomed Sci Appl       Date:  2001-04-25

4.  Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients.

Authors:  François Becher; Alain G Pruvost; Dimitri D Schlemmer; Christophe A Créminon; Cecile M Goujard; Jean François Delfraissy; Henri C Benech; Jacques J Grassi
Journal:  AIDS       Date:  2003-03-07       Impact factor: 4.177

5.  Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.

Authors:  J F Rodriguez; J L Rodriguez; J Santana; H García; O Rosario
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

6.  Improved method for the simultaneous determination of d4T, 3TC and ddl intracellular phosphorylated anabolites in human peripheral-blood mononuclear cells using high-performance liquid chromatography/tandem mass spectrometry.

Authors:  François Becher; Alain Pruvost; Cécile Goujard; Catherine Guerreiro; J-F Delfraissy; Jacques Grassi; Henri Benech
Journal:  Rapid Commun Mass Spectrom       Date:  2002       Impact factor: 2.419

Review 7.  Intracellular studies of the nucleoside reverse transcriptase inhibitor active metabolites: a review.

Authors:  J F Rodriguez Orengo; J Santana; I Febo; C Diaz; J L Rodriguez; R Garcia; E Font; O Rosario
Journal:  P R Health Sci J       Date:  2000-03       Impact factor: 0.705

8.  Lack of evidence for in vivo transformation of zidovudine triphosphate to stavudine triphosphate in human immunodeficiency virus-infected patients.

Authors:  Margarita Meléndez; Raúl Blanco; Wilfredo Delgado; Rosario García; Jorge Santana; Hermes García; Osvaldo Rosario; José F Rodríguez
Journal:  Antimicrob Agents Chemother       Date:  2006-03       Impact factor: 5.191

9.  Interferon-ribavirin in association with stavudine has no impact on plasma human immunodeficiency virus (HIV) type 1 level in patients coinfected with HIV and hepatitis C virus: a CORIST-ANRS HC1 trial.

Authors:  Dominique Salmon-Céron; Régis Lassalle; Alain Pruvost; Henri Benech; Magali Bouvier-Alias; Christopher Payan; Cécile Goujard; Eric Bonnet; Fabien Zoulim; Philippe Morlat; Philippe Sogni; Sophie Pérusat; Jean-Marc Tréluyer; Geneviève Chêne
Journal:  Clin Infect Dis       Date:  2003-05-09       Impact factor: 9.079

10.  Determination of adenosine nucleotides in cultured cells by ion-pairing liquid chromatography-electrospray ionization mass spectrometry.

Authors:  Tianxiu Qian; Zongwei Cai; M S Yang
Journal:  Anal Biochem       Date:  2004-02-01       Impact factor: 3.365
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  2 in total

1.  Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.

Authors:  Delia Susan-Resiga; Alice T Bentley; Matthew D Lynx; Darcy D LaClair; Edward E McKee
Journal:  Antimicrob Agents Chemother       Date:  2007-01-12       Impact factor: 5.191

2.  Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics.

Authors:  Anthony R Vortherms; Robert P Doyle; Dayuan Gao; Olivia Debrah; Patrick J Sinko
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2008-02       Impact factor: 1.381
  2 in total

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