Literature DB >> 16870795

Cysteine proteinase inhibitors in murine cysticercosis.

Salman Baig1, Raymond T Damian, Jorge Morales-Montor, Rupal Thazhath, Amr Ghaleb, Meredith Welch, Jamil Talhouk, A Clinton White.   

Abstract

We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

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Year:  2006        PMID： 16870795      PMCID： PMC1538644          DOI： 10.1128/AAC.01060-05

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Characterization of a cysteine proteinase from Taenia crassiceps cysts.

Authors:  A C White; S Baig; C L Chappell
Journal:  Mol Biochem Parasitol       Date:  1997-04       Impact factor: 1.759

2.  Purification and characterization of a metacestode cysteine proteinase from Taenia solium involved in the breakdown of human IgG.

Authors:  S Baig; R T Damian; J L Molinari; P Tato; J Morales-Montor; M Welch; J Talhouk; R Hashmeys; A C White
Journal:  Parasitology       Date:  2005-09       Impact factor: 3.234

Review 3.  Cysteine protease inhibitors as chemotherapy for parasitic infections.

Authors:  J H McKerrow; J C Engel; C R Caffrey
Journal:  Bioorg Med Chem       Date:  1999-04       Impact factor: 3.641

4.  The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum.

Authors:  E A Hughes; B Ortmann; M Surman; P Cresswell
Journal:  J Exp Med       Date:  1996-04-01       Impact factor: 14.307

5.  The marketing of cysticercotic pigs in the Sierra of Peru. The Cysticercosis Working Group in Peru.

Authors: 
Journal:  Bull World Health Organ       Date:  1993       Impact factor: 9.408

6.  Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel.

Authors:  Patrick G Yeni; Scott M Hammer; Martin S Hirsch; Michael S Saag; Mauro Schechter; Charles C J Carpenter; Margaret A Fischl; Jose M Gatell; Brian G Gazzard; Donna M Jacobsen; David A Katzenstein; Julio S G Montaner; Douglas D Richman; Robert T Schooley; Melanie A Thompson; Stefano Vella; Paul A Volberding
Journal:  JAMA       Date:  2004-07-14       Impact factor: 56.272

7.  A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis.

Authors:  Héctor H Garcia; E Javier Pretell; Robert H Gilman; S Manuel Martinez; Lawrence H Moulton; Oscar H Del Brutto; Genaro Herrera; Carlton A W Evans; Armando E Gonzalez
Journal:  N Engl J Med       Date:  2004-01-15       Impact factor: 91.245

8.  Albendazole in neurocysticercosis.

Authors:  M V Padma; M Behari; N K Misra; G K Ahuja
Journal:  Natl Med J India       Date:  1995 Nov-Dec       Impact factor: 0.537

Review 9.  Current consensus guidelines for treatment of neurocysticercosis.

Authors:  Hector H García; Carlton A W Evans; Theodore E Nash; Osvaldo M Takayanagui; A Clinton White; David Botero; Vedantam Rajshekhar; Victor C W Tsang; Peter M Schantz; James C Allan; Ana Flisser; Dolores Correa; Elsa Sarti; Jon S Friedland; S Manuel Martinez; Armando E Gonzalez; Robert H Gilman; Oscar H Del Brutto
Journal:  Clin Microbiol Rev       Date:  2002-10       Impact factor: 26.132

10.  Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection.

Authors:  J C Engel; P S Doyle; I Hsieh; J H McKerrow
Journal:  J Exp Med       Date:  1998-08-17       Impact factor: 14.307
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