Literature DB >> 16870776

Peptide immunization as an adjuvant to chemotherapy in mice challenged intratracheally with virulent yeast cells of Paracoccidioides brasiliensis.

A F Marques1, M B da Silva, M A P Juliano, L R Travassos, C P Taborda.   

Abstract

Immunization with peptide P10, derived from gp43, and chemotherapy were used together in an attempt to improve treatment of paracoccidioidomycosis and prevent relapses. The combined treatment showed an additive protective effect when administered at 48 h or 30 days after intratracheal challenge. Its use is recommended to improve regular chemotherapy and reduce the duration of treatment.

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Year:  2006        PMID： 16870776      PMCID： PMC1538653          DOI： 10.1128/AAC.00220-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  [In vitro action of amphotericin B on Paracoccidioides brasiliensis].

Authors:  C S DA LACAZ; C M ULSON; A DE PRADO SAMPAIO S
Journal:  Rev Paul Med       Date:  1959-05

2.  In vitro evaluation of voriconazole against some clinically important fungi.

Authors:  M R McGinnis; L Pasarell; D A Sutton; A W Fothergill; C R Cooper; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

3.  DNA-based vaccination against murine paracoccidioidomycosis using the gp43 gene from paracoccidioides brasiliensis.

Authors:  A R Pinto; R Puccia; S N Diniz; M F Franco; L R Travassos
Journal:  Vaccine       Date:  2000-07-01       Impact factor: 3.641

4.  In vitro susceptibility of Paracoccidioides brasiliensis yeast form to antifungal agents.

Authors:  A Restrepo; C de B Tabares
Journal:  Rev Inst Med Trop Sao Paulo       Date:  1984 Nov-Dec       Impact factor: 1.846

5.  Mapping of the T-cell epitope in the major 43-kilodalton glycoprotein of Paracoccidioides brasiliensis which induces a Th-1 response protective against fungal infection in BALB/c mice.

Authors:  C P Taborda; M A Juliano; R Puccia; M Franco; L R Travassos
Journal:  Infect Immun       Date:  1998-02       Impact factor: 3.441

6.  In vivo and in vitro characteristics of six Paracoccidioides brasiliensis strains.

Authors:  S S Kashino; V L Calich; E Burger; L M Singer-Vermes
Journal:  Mycopathologia       Date:  1985-12       Impact factor: 2.574

7.  Synthesis and immunological activity of a branched peptide carrying the T-cell epitope of gp43, the major exocellular antigen of Paracoccidioides brasiliensis.

Authors:  C P Taborda; C R Nakaie; E M Cilli; E G Rodrigues; L S Silva; M F Franco; L R Travassos
Journal:  Scand J Immunol       Date:  2004-01       Impact factor: 3.487

8.  Biochemical serogrouping of clinical isolates of Cryptococcus neoformans.

Authors:  H J Shadomy; S Wood-Helie; S Shadomy; W E Dismukes; R Y Chau
Journal:  Diagn Microbiol Infect Dis       Date:  1987-02       Impact factor: 2.803

9.  In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals.

Authors:  Leo Kei Iwai; Márcia Yoshida; John Sidney; Maria Aparecida Shikanai-Yasuda; Anna Carla Goldberg; Maria Aparecida Juliano; Jurgen Hammer; Luiz Juliano; Alessandro Sette; Jorge Kalil; Luiz Rodolpho Travassos; Edecio Cunha-Neto
Journal:  Mol Med       Date:  2003 Sep-Dec       Impact factor: 6.354

10.  A preliminary study of in vitro antibiotic activity of saperconazole and other azoles on Paracoccidioides brasiliensis.

Authors:  G San-Blas; A M Calcagno; F San-Blas
Journal:  J Med Vet Mycol       Date:  1993
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  25 in total

1.  Protective effect of rPb40 as an adjuvant for chemotherapy in experimental paracoccidioidomycosis.

Authors:  V C Fernandes; E M N Martins; J N Boeloni; R Serakides; A M Goes
Journal:  Mycopathologia       Date:  2012-03-03       Impact factor: 2.574

2.  T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals.

Authors:  Leo Kei Iwai; Márcia Yoshida; Aya Sadahiro; Washington Robert da Silva; Maria Lucia Marin; Anna Carla Goldberg; Maria Aparecida Juliano; Luiz Juliano; Maria Aparecida Shikanai-Yasuda; Jorge Kalil; Edecio Cunha-Neto; Luiz R Travassos
Journal:  Clin Vaccine Immunol       Date:  2007-02-28

Review 3.  Paracoccidioidomycosis vaccine.

Authors:  Luiz R Travassos; Carlos P Taborda
Journal:  Hum Vaccin Immunother       Date:  2012-08-16       Impact factor: 3.452

4.  Mice immunization with radioattenuated yeast cells of Paracoccidiodes brasiliensis: influence of the number of immunizations.

Authors:  Estefânia Mara do Nascimento Martins; Bernardo Sgarbi Reis; Maria Aparecida de Resende; Antero Silva Ribeiro de Andrade; Alfredo Miranda Goes
Journal:  Mycopathologia       Date:  2009-04-07       Impact factor: 2.574

5.  Vaccination with heat shock protein 60 induces a protective immune response against experimental Paracoccidioides brasiliensis pulmonary infection.

Authors:  Renata de Bastos Ascenço Soares; Francisco J Gomez; Célia Maria de Almeida Soares; George S Deepe
Journal:  Infect Immun       Date:  2008-07-14       Impact factor: 3.441

6.  Use of recombinant gp43 isoforms expressed in Pichia pastoris for diagnosis of paracoccidioidomycosis.

Authors:  K C Carvalho; M C Vallejo; Z P Camargo; R Puccia
Journal:  Clin Vaccine Immunol       Date:  2008-01-30

Review 7.  Attempts at a peptide vaccine against paracoccidioidomycosis, adjuvant to chemotherapy.

Authors:  Luiz R Travassos; Elaine G Rodrigues; Leo K Iwai; Carlos P Taborda
Journal:  Mycopathologia       Date:  2008 Apr-May       Impact factor: 2.574

Review 8.  Diversity in Paracoccidioides brasiliensis. The PbGP43 gene as a genetic marker.

Authors:  Rosana Puccia; Juan G McEwen; Patrícia S Cisalpino
Journal:  Mycopathologia       Date:  2008 Apr-May       Impact factor: 2.574

9.  DNA-hsp65 vaccine as therapeutic strategy to treat experimental chromoblastomycosis caused by Fonsecaea pedrosoi.

Authors:  Isaque Medeiros Siqueira; Alice Melo Ribeiro; Yanna Karla de Medeiros Nóbrega; Karina Smidt Simon; Ana Camila Oliveira Souza; Márcio Souza Jerônimo; Florêncio Figueiredo Cavalcante Neto; Célio Lopes Silva; Maria Sueli Soares Felipe; Anamélia Lorenzetti Bocca
Journal:  Mycopathologia       Date:  2012-11-22       Impact factor: 2.574

10.  Cyclopalladated Compound 7a Induces Apoptosis- and Autophagy-Like Mechanisms in Paracoccidioides and Is a Candidate for Paracoccidioidomycosis Treatment.

Authors:  Denise C Arruda; Alisson L Matsuo; Luiz S Silva; Fernando Real; Natanael P Leitão; Jhon H S Pires; Antonio Carlos F Caires; Daniel M Garcia; Fernanda F M Cunha; Rosana Puccia; Larissa V G Longo
Journal:  Antimicrob Agents Chemother       Date:  2015-09-08       Impact factor: 5.191
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