Literature DB >> 16870662

Driving ability in sleep apnoea patients before and after CPAP treatment: evaluation on a road safety platform.

S Mazza1, J-L Pépin, B Naëgelé, E Rauch, C Deschaux, P Ficheux, P Lévy.   

Abstract

Sleepiness is considered to be the major cause of increased traffic accidents in patients with obstructive sleep apnoea syndrome (OSAS). Until now, OSAS patients' driving ability has been assessed using driving simulators, but no assessment in a more natural driving environment has been carried out to date. The aim of the present study was to evaluate driving parameters in OSAS and in controls on a road safety platform, and to compare them with attentional in-laboratory measures before and after continuous positive airway pressure treatment. The parameters measured were: reaction time; distance to stop and number of collisions on the platform; maintenance of wakefulness; and sustained, selective and divided attention in laboratory. Patients exhibited much longer reaction times than controls, leading to a lengthening of the vehicle's stopping distance of 8.8 m at 40 km.h(-1) and to twice the number of collisions. Patients did not demonstrate objective sleepiness or selective and sustained attention deficits. Divided attention deficits were found. However, they did not allow the prediction of real driving impairment. After CPAP treatment, there was no longer any difference between patients and controls regarding driving and attention performances. Driving abilities are significantly impaired in obstructive sleep apnoea syndrome. After continuous positive airway pressure treatment, deficits were normalised. This stresses the importance of evaluating attentional parameters in apnoeic patients and of offering continuous positive airway pressure treatment even to non-sleepy subjects.

Entities:  

Mesh:

Year:  2006        PMID: 16870662     DOI: 10.1183/09031936.06.00112905

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


  14 in total

1.  Reliability of a single objective measure in assessing sleepiness.

Authors:  Bernie Y Sunwoo; Nicholas Jackson; Greg Maislin; Indira Gurubhagavatula; Charles F George; Allan I Pack
Journal:  Sleep       Date:  2012-01-01       Impact factor: 5.849

Review 2.  Sleep-disordered breathing and cognition in older adults.

Authors:  Molly E Zimmerman; Mark S Aloia
Journal:  Curr Neurol Neurosci Rep       Date:  2012-10       Impact factor: 5.081

3.  Can the MSLT be a useful tool to assess motor vehicle crash risk in sleepy drivers?

Authors:  Pierre Philip
Journal:  Sleep       Date:  2010-06       Impact factor: 5.849

4.  Driving simulator performance remains impaired in patients with severe OSA after CPAP treatment.

Authors:  Andrew Vakulin; Stuart D Baulk; Peter G Catcheside; Nick A Antic; Cameron J van den Heuvel; Jillian Dorrian; R Doug McEvoy
Journal:  J Clin Sleep Med       Date:  2011-06-15       Impact factor: 4.062

5.  Auto bi-level with pressure relief during exhalation as a rescue therapy for optimally treated obstructive sleep apnoea patients with poor compliance to continuous positive airways pressure therapy--a pilot study.

Authors:  Thibaut Gentina; Francois Fortin; Bernard Douay; Jean Marc Dernis; Frederic Herengt; Jean Christophe Bout; Catherine Lamblin
Journal:  Sleep Breath       Date:  2010-03-04       Impact factor: 2.816

6.  A Cost-Effectiveness Analysis of Surgery for Middle-Aged Men with Severe Obstructive Sleep Apnea Intolerant of CPAP.

Authors:  Kelvin B Tan; Song Tar Toh; Christian Guilleminault; Jon-Erik C Holty
Journal:  J Clin Sleep Med       Date:  2015-04-15       Impact factor: 4.062

Review 7.  Neurocognitive effects of obstructive sleep apnea syndrome.

Authors:  Edwin Verstraeten
Journal:  Curr Neurol Neurosci Rep       Date:  2007-03       Impact factor: 5.081

8.  Modafinil improves real driving performance in patients with hypersomnia: a randomized double-blind placebo-controlled crossover clinical trial.

Authors:  Pierre Philip; Cyril Chaufton; Jacques Taillard; Aurore Capelli; Olivier Coste; Damien Léger; Nicholas Moore; Patricia Sagaspe
Journal:  Sleep       Date:  2014-03-01       Impact factor: 5.849

9.  Relationship between obstructive sleep apnea severity and brain activation during a sustained attention task.

Authors:  Liat Ayalon; Sonia Ancoli-Israel; Allison A Aka; Benjamin S McKenna; Sean P A Drummond
Journal:  Sleep       Date:  2009-03       Impact factor: 5.849

Review 10.  Treatment of narcolepsy and other hypersomnias of central origin.

Authors:  Merrill S Wise; Donna L Arand; R Robert Auger; Stephen N Brooks; Nathaniel F Watson
Journal:  Sleep       Date:  2007-12       Impact factor: 5.849

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.