Literature DB >> 16870547

The effects of microdose recombinant human erythropoietin regimens in athletes.

Michael Ashenden, Emmanuelle Varlet-Marie, Françoise Lasne, Michel Audran.   

Abstract

This study appraised the veracity of claims that athletes can evade doping controls by injecting microdoses of recombinant human erythropoietin (rHuEPO), which rapidly disappear from the circulation. We confirmed that microdosing can reduce the window of detection to as little as 12-18 hours post-injection, suggesting that authorities must adopt appropriate counter measures.

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Year:  2006        PMID: 16870547

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  4 in total

1.  Screening for recombinant human erythropoietin using [Hb], reticulocytes, the OFF(hr score), OFF(z score) and Hb(z score): status of the Blood Passport.

Authors:  Andreas Bornø; Niels J Aachmann-Andersen; Thor Munch-Andersen; Carl J Hulston; Carsten Lundby
Journal:  Eur J Appl Physiol       Date:  2010-02-02       Impact factor: 3.078

2.  Current markers of the Athlete Blood Passport do not flag microdose EPO doping.

Authors:  Michael Ashenden; Clare E Gough; Andrew Garnham; Christopher J Gore; Ken Sharpe
Journal:  Eur J Appl Physiol       Date:  2011-02-20       Impact factor: 3.078

Review 3.  Altitude and Erythropoietin: Comparative Evaluation of Their Impact on Key Parameters of the Athlete Biological Passport: A Review.

Authors:  Jonas J Saugy; Tania Schmoutz; Francesco Botrè
Journal:  Front Sports Act Living       Date:  2022-06-30

Review 4.  Erythropoiesis-stimulating agents and other methods to enhance oxygen transport.

Authors:  S Elliott
Journal:  Br J Pharmacol       Date:  2008-03-24       Impact factor: 8.739

  4 in total

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