Literature DB >> 16869765

The evolving portrait of cancer metastasis.

P B Gupta1, S Mani, J Yang, K Hartwell, R A Weinberg.   

Abstract

The phenomenon of cancer metastasis remains poorly understood. We discuss here various conceptual frameworks that attempt to rationalize the mechanisms by which tumors acquire metastatic ability. Portrayal of cancer as a somatic Darwinian process occurring within a tissue fails to fully explain the phenomenon of metastatic competence. The biology of pre-neoplastic cells also complicates this picture, since the phenotypes of normal cellular precursors are clearly relevant to metastatic behavior following transformation. Recent experimental results help to shed light on these and other considerations regarding the molecular mechanisms of malignant progression.

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Year:  2005        PMID： 16869765     DOI： 10.1101/sqb.2005.70.033

Source DB:  PubMed          Journal:  Cold Spring Harb Symp Quant Biol        ISSN： 0091-7451


  26 in total

1.  CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.

Authors:  Aldo M Roccaro; Yuji Mishima; Antonio Sacco; Michele Moschetta; Yu-Tzu Tai; Jiantao Shi; Yong Zhang; Michaela R Reagan; Daisy Huynh; Yawara Kawano; Ilyas Sahin; Marco Chiarini; Salomon Manier; Michele Cea; Yosra Aljawai; Siobhan Glavey; Elizabeth Morgan; Chin Pan; Franziska Michor; Pina Cardarelli; Michelle Kuhne; Irene M Ghobrial
Journal:  Cell Rep       Date:  2015-07-16       Impact factor: 9.423

2.  Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression.

Authors:  Byoungduck Park; Bokyung Sung; Vivek R Yadav; Sung-Gook Cho; Mingyao Liu; Bharat B Aggarwal
Journal:  Int J Cancer       Date:  2011-03-29       Impact factor: 7.396

3.  miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis.

Authors:  Avital Gaziel-Sovran; Miguel F Segura; Raffaella Di Micco; Mary K Collins; Douglas Hanniford; Eleazar Vega-Saenz de Miera; John F Rakus; John F Dankert; Shulian Shang; Robert S Kerbel; Nina Bhardwaj; Yongzhao Shao; Farbod Darvishian; Jiri Zavadil; Adrian Erlebacher; Lara K Mahal; Iman Osman; Eva Hernando
Journal:  Cancer Cell       Date:  2011-07-12       Impact factor: 31.743

4.  Genome remodeling upon mesenchymal tumor cell fusion contributes to tumor progression and metastatic spread.

Authors:  Lydia Lartigue; Candice Merle; Pauline Lagarde; Lucile Delespaul; Tom Lesluyes; Sophie Le Guellec; Gaelle Pérot; Laura Leroy; Jean-Michel Coindre; Frédéric Chibon
Journal:  Oncogene       Date:  2020-04-02       Impact factor: 9.867

5.  Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

Authors:  Christine Gjerdrum; Crina Tiron; Torill Høiby; Ingunn Stefansson; Hallvard Haugen; Tone Sandal; Karin Collett; Shan Li; Emmet McCormack; Bjørn Tore Gjertsen; David R Micklem; Lars A Akslen; Carlotta Glackin; James B Lorens
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-28       Impact factor: 11.205

Review 6.  Pancreatic cancer: Are "liquid biopsies" ready for prime-time?

Authors:  Alexandra R Lewis; Juan W Valle; Mairead G McNamara
Journal:  World J Gastroenterol       Date:  2016-08-28       Impact factor: 5.742

7.  High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish.

Authors:  Konstantin Stoletov; Valerie Montel; Robin D Lester; Steven L Gonias; Richard Klemke
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-22       Impact factor: 11.205

8.  Biological functions of the genes in the mammaprint breast cancer profile reflect the hallmarks of cancer.

Authors:  Sun Tian; Paul Roepman; Laura J Van't Veer; Rene Bernards; Femke de Snoo; Annuska M Glas
Journal:  Biomark Insights       Date:  2010-11-28

9.  Use of Radioiodinated Peptide Arg-Arg-Leu Targeted to Neovasculari- zation as well as Tumor Cells in Molecular Tumor Imaging.

Authors:  Xia Lu; Ping Yan; Rong-Fu Wang; Meng Liu; Ming-Ming Yu; Chun-Li Zhang
Journal:  Chin J Cancer Res       Date:  2012-03       Impact factor: 5.087

10.  Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT Inhibitors.

Authors:  Milica Vucetic; Boutaina Daher; Shamir Cassim; Scott Parks; Jacques Pouyssegur
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622
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