Literature DB >> 16869630

Total synthesis of (-)-spongidepsin.

Laurent Ferrié1, Sébastien Reymond, Patrice Capdevielle, Janine Cossy.   

Abstract

[structure: see text] A convergent and rapid stereoselective synthesis of (-)-spongidepsin has been achieved from the Roche ester in 14 steps with an overall yield of 13%.

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Year:  2006        PMID: 16869630     DOI: 10.1021/ol061029w

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  6 in total

1.  Fully reagent-controlled asymmetric synthesis of (-)-spongidepsin via the Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction).

Authors:  Gangguo Zhu; Ei-ichi Negishi
Journal:  Org Lett       Date:  2007-06-21       Impact factor: 6.005

2.  Enantioselective homocrotylboration of aliphatic aldehydes.

Authors:  Hongkun Lin; Wenbo Pei; Hao Wang; Kendall N Houk; Isaac J Krauss
Journal:  J Am Chem Soc       Date:  2012-12-26       Impact factor: 15.419

3.  Cyclodepsipeptides from marine sponges: natural agents for drug research.

Authors:  Gowri Shankar Bagavananthem Andavan; Rosa Lemmens-Gruber
Journal:  Mar Drugs       Date:  2010-03-22       Impact factor: 5.118

4.  Iridium-catalyzed enantioselective allylic substitution of unstabilized enolates derived from α,β-unsaturated ketones.

Authors:  Ming Chen; John F Hartwig
Journal:  Angew Chem Int Ed Engl       Date:  2014-06-10       Impact factor: 15.336

5.  Dinuclear zinc-catalyzed asymmetric desymmetrization of acyclic 2-substituted-1,3-propanediols: a powerful entry into chiral building blocks.

Authors:  Barry M Trost; Sushant Malhotra; Takashi Mino; Naomi S Rajapaksa
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

6.  Diastereo- and Enantioselective Access to Stereotriads through a Flexible Coupling of Substituted Aldehydes and Alkenes.

Authors:  Jing Li; Alexander Preinfalk; Nuno Maulide
Journal:  Angew Chem Int Ed Engl       Date:  2019-03-27       Impact factor: 15.336

  6 in total

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