Literature DB >> 16868450

Foxp3+ regulatory T cells in antiretroviral-naive HIV patients.

Martin Montes1, Dorothy E Lewis, Cesar Sanchez, Diego Lopez de Castilla, Edward A Graviss, Carlos Seas, Eduardo Gotuzzo, A Clinton White.   

Abstract

We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/microl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

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Year:  2006        PMID： 16868450     DOI： 10.1097/01.aids.0000238415.98194.38

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  21 in total

1.  Normalization of FoxP3(+) regulatory T cells in response to effective antiretroviral therapy.

Authors:  Martin Montes; Cesar Sanchez; Dorothy E Lewis; Edward A Graviss; Carlos Seas; Eduardo Gotuzzo; A Clinton White
Journal:  J Infect Dis       Date:  2010-12-21       Impact factor: 5.226

2.  Altered frequency and phenotype of CD4+ forkhead box protein 3+ T cells and its association with autoantibody production in human immunodeficiency virus-infected paediatric patients.

Authors:  R J Argüello; J Balbaryski; G Barboni; M Candi; E Gaddi; S Laucella
Journal:  Clin Exp Immunol       Date:  2012-05       Impact factor: 4.330

3.  Early and long-lasting alteration of effector CD45RA(-)Foxp3(high) regulatory T-cell homeostasis during HIV infection.

Authors:  Federico Simonetta; Camille Lecuroux; Isabelle Girault; Cécile Goujard; Martine Sinet; Olivier Lambotte; Alain Venet; Christine Bourgeois
Journal:  J Infect Dis       Date:  2012-03-28       Impact factor: 5.226

4.  Level, phenotype and activation status of CD4+FoxP3+ regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus.

Authors:  N I Rallón; M López; V Soriano; J García-Samaniego; M Romero; P Labarga; P García-Gasco; J González-Lahoz; J M Benito
Journal:  Clin Exp Immunol       Date:  2009-01       Impact factor: 4.330

5.  Regulatory T cell expansion and immune activation during untreated HIV type 1 infection are associated with disease progression.

Authors:  Weiwei Cao; Beth D Jamieson; Lance E Hultin; Patricia M Hultin; Roger Detels
Journal:  AIDS Res Hum Retroviruses       Date:  2009-02       Impact factor: 2.205

6.  Multi-analyte profiling of ten cytokines in South African HIV-infected patients with Immune Reconstitution Inflammatory Syndrome (IRIS).

Authors:  Catherine M Worsley; Melinda S Suchard; Wendy S Stevens; Annelies Van Rie; David M Murdoch
Journal:  AIDS Res Ther       Date:  2010-10-07       Impact factor: 2.250

7.  FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity.

Authors:  Melinda S Suchard; Elizabeth Mayne; Victoria A Green; Sharon Shalekoff; Samantha L Donninger; Wendy S Stevens; Clive M Gray; Caroline T Tiemessen
Journal:  PLoS One       Date:  2010-07-23       Impact factor: 3.240

8.  Role of common gamma chain utilizing cytokines for immune reconstitution in HIV infection.

Authors:  Savita Pahwa
Journal:  Immunol Res       Date:  2007       Impact factor: 2.829

9.  The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8+ T cells in HIV-1-infected typical progressors, but not in long-term non-progressors.

Authors:  Yanmei Jiao; JunLiang Fu; Shaojun Xing; Baoyun Fu; Zheng Zhang; Ming Shi; Xicheng Wang; Jiyuan Zhang; Lei Jin; Fubiao Kang; Hao Wu; Fu-Sheng Wang
Journal:  Immunology       Date:  2008-11-07       Impact factor: 7.397

10.  Increased levels of regulatory T cells (Tregs) in human immunodeficiency virus-infected patients after 5 years of highly active anti-retroviral therapy may be due to increased thymic production of naive Tregs.

Authors:  L Kolte; J C Gaardbo; K Skogstrand; L P Ryder; A K Ersbøll; S D Nielsen
Journal:  Clin Exp Immunol       Date:  2008-11-06       Impact factor: 4.330
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