| Literature DB >> 16867876 |
Kathleen M Tatti1, Wun-Ju Shieh, Sonya Phillips, Michael Augenbraun, Chandrakant Rao, Sherif R Zaki.
Abstract
Histopathology and special stains of a brain biopsy specimen from a 42-year-old man revealed numerous gram-positive bacilli arranged in branching filaments, suggesting Nocardia infection. Antibiotic therapy with trimethoprim-sulfamethoxazole markedly decreased the abscess size, and the patient improved. DNA was analyzed from formalin-fixed sections of the cerebral abscess by a 16S ribosomal DNA polymerase chain reaction assay demonstrating the presence of either Nocardia farcinica or N otitidiscaviarum. A species-specific polymerase chain reaction assay confirmed N farcinica as the etiologic agent.Entities:
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Year: 2006 PMID: 16867876 DOI: 10.1016/j.humpath.2006.02.019
Source DB: PubMed Journal: Hum Pathol ISSN: 0046-8177 Impact factor: 3.466