Literature DB >> 16867522

The determination of torasemide and metabolites in plasma by high-performance liquid chromatography.

E Besenfelder1.   

Abstract

A high-performance liquid chromatographic method for the determination of torasemide and two active metabolites is described. The assay uses a reversed-phase gradient system and UV-detection. Sample preparation includes deproteinisation and liquid-solid extraction incorporating an internal standard. Data on recovery, detection limits, precision and accuracy are presented. The presence of an unidentified metabolite also is reported.

Entities:  

Year:  1987        PMID： 16867522     DOI： 10.1016/0731-7085(87)80029-8

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  4 in total

Review 1.  Clinical pharmacokinetics and pharmacodynamics of torasemide.

Authors:  H Knauf; E Mutschler
Journal:  Clin Pharmacokinet       Date:  1998-01       Impact factor: 6.447

Review 2.  Torasemide. A review of its pharmacological properties and therapeutic potential.

Authors:  H A Friedel; M M Buckley
Journal:  Drugs       Date:  1991-01       Impact factor: 9.546

3.  Pharmacokinetics of torasemide and its metabolites in end-stage renal disease.

Authors:  B K Krämer; A Schwab; N Braun; F Strutz; G A Müller; T Risler
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

4.  Determination of torasemide in human plasma and its bioequivalence study by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.

Authors:  Lin Zhang; Rulin Wang; Yuan Tian; Zunjian Zhang
Journal:  J Pharm Anal       Date:  2015-11-11
  4 in total

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