Literature DB >> 16867507

Determination of pilocarpine by HPLC in presence of isopilocarpine a pH-sensitive polymer in ophthalmic dispersions.

H Ibrahim1, T Boye, M Wermeille, R Gurny, P Buri.   

Abstract

Quantification of pilocarpine in the presence of the epimer isopilocarpine in polymeric dispersions is reported. The method describes a technique using reversed-phase HPLC and UV detection of pilocarpine in the presence of a pH-sensitive polymer. As this method does not require prior sample preparation it will be of special interest for process control and development.

Entities:  

Year:  1987        PMID: 16867507     DOI: 10.1016/0731-7085(87)80044-4

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  1 in total

1.  Decomposition of pilocarpine eye drops assessed by a highly efficient high pressure liquid chromatographic method.

Authors:  P F Kuks; L E Weekers; P B Goldhoorn
Journal:  Pharm Weekbl Sci       Date:  1990-10-19
  1 in total

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