Literature DB >> 16864783

Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function.

Chenguang Wang1, Zhiping Li, Yinan Lu, Runlei Du, Sanjay Katiyar, Jianguo Yang, Maofu Fu, Jennifer E Leader, Andrew Quong, Phyllis M Novikoff, Richard G Pestell.   

Abstract

Cyclin D1 promotes nuclear DNA synthesis through phosphorylation and inactivation of the pRb tumor suppressor. Herein, cyclin D1 deficiency increased mitochondrial size and activity that was rescued by cyclin D1 in a Cdk-dependent manner. Nuclear respiratory factor 1 (NRF-1), which induces nuclear-encoded mitochondrial genes, was repressed in expression and activity by cyclin D1. Cyclin D1-dependent kinase phosphorylates NRF-1 at S47. Cyclin D1 abundance thus coordinates nuclear DNA synthesis and mitochondrial function.

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Year:  2006        PMID： 16864783      PMCID： PMC1518800          DOI： 10.1073/pnas.0603363103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  40 in total

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Authors:  Richard C Scarpulla
Journal:  Biochim Biophys Acta       Date:  2002-06-07

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Authors:  A T Reutens; M Fu; C Wang; C Albanese; M J McPhaul; Z Sun; S P Balk; O A Jänne; J J Palvimo; R G Pestell
Journal:  Mol Endocrinol       Date:  2001-05

3.  CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation.

Authors:  T Arnould; S Vankoningsloo; P Renard; A Houbion; N Ninane; C Demazy; J Remacle; M Raes
Journal:  EMBO J       Date:  2002-01-15       Impact factor: 11.598

4.  Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.

Authors:  C Albanese; M D'Amico; A T Reutens; M Fu; G Watanabe; R J Lee; R N Kitsis; B Henglein; M Avantaggiati; K Somasundaram; B Thimmapaya; R G Pestell
Journal:  J Biol Chem       Date:  1999-11-26       Impact factor: 5.157

5.  Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species.

Authors:  Clara Schroedl; David S McClintock; G R Scott Budinger; Navdeep S Chandel
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2002-11       Impact factor: 5.464

6.  Specific protection against breast cancers by cyclin D1 ablation.

Authors:  Q Yu; Y Geng; P Sicinski
Journal:  Nature       Date:  2001-06-28       Impact factor: 49.962

7.  Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation.

Authors:  J R Alt; J L Cleveland; M Hannink; J A Diehl
Journal:  Genes Dev       Date:  2000-12-15       Impact factor: 11.361

8.  Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells.

Authors:  U Andersson; R C Scarpulla
Journal:  Mol Cell Biol       Date:  2001-06       Impact factor: 4.272

9.  Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.

Authors:  Chenguang Wang; Nagarajan Pattabiraman; Jian Nian Zhou; Maofu Fu; Toshiyuki Sakamaki; Chris Albanese; Zhiping Li; Kongming Wu; James Hulit; Peter Neumeister; Phyllis M Novikoff; Michael Brownlee; Philipp E Scherer; Joan G Jones; Kathleen D Whitney; Lawrence A Donehower; Emily L Harris; Thomas Rohan; David C Johns; Richard G Pestell
Journal:  Mol Cell Biol       Date:  2003-09       Impact factor: 4.272

10.  Cyclin D1 governs adhesion and motility of macrophages.

Authors:  Peter Neumeister; Fiona J Pixley; Ying Xiong; Huafeng Xie; Kongming Wu; Anthony Ashton; Michael Cammer; Amanda Chan; Marc Symons; E Richard Stanley; Richard G Pestell
Journal:  Mol Biol Cell       Date:  2003-02-21       Impact factor: 4.138
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  106 in total

1.  S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.

Authors:  Catherine Espeillac; Claudia Mitchell; Séverine Celton-Morizur; Céline Chauvin; Vonda Koka; Cynthia Gillet; Jeffrey H Albrecht; Chantal Desdouets; Mario Pende
Journal:  J Clin Invest       Date:  2011-07       Impact factor: 14.808

Review 2.  Mitochondrial regulation of cell cycle and proliferation.

Authors:  Valeria Gabriela Antico Arciuch; María Eugenia Elguero; Juan José Poderoso; María Cecilia Carreras
Journal:  Antioxid Redox Signal       Date:  2012-01-13       Impact factor: 8.401

3.  ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice.

Authors:  Mathew C Casimiro; Marco Crosariol; Emanuele Loro; Adam Ertel; Zuoren Yu; William Dampier; Elizabeth A Saria; Alex Papanikolaou; Timothy J Stanek; Zhiping Li; Chenguang Wang; Paolo Fortina; Sankar Addya; Aydin Tozeren; Erik S Knudsen; Andrew Arnold; Richard G Pestell
Journal:  J Clin Invest       Date:  2012-02-06       Impact factor: 14.808

4.  RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.

Authors:  Ross A Poché; Min Zhang; Elda M Rueda; Xuefei Tong; Melissa L McElwee; Leeyean Wong; Chih-Wei Hsu; Marion Dejosez; Alan R Burns; Donald A Fox; James F Martin; Thomas P Zwaka; Mary E Dickinson
Journal:  Cell Rep       Date:  2016-02-11       Impact factor: 9.423

Review 5.  Estrogens regulate life and death in mitochondria.

Authors:  Carolyn M Klinge
Journal:  J Bioenerg Biomembr       Date:  2017-08       Impact factor: 2.945

6.  Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis.

Authors:  Vijay G Sankaran; Stuart H Orkin; Carl R Walkley
Journal:  Genes Dev       Date:  2008-02-07       Impact factor: 11.361

7.  Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint.

Authors:  Xiaoming Ju; Mathew C Casimiro; Michael Gormley; Hui Meng; Xuanmao Jiao; Sanjay Katiyar; Marco Crosariol; Ke Chen; Min Wang; Andrew A Quong; Michael P Lisanti; Adam Ertel; Richard G Pestell
Journal:  Cancer Res       Date:  2013-11-26       Impact factor: 12.701

8.  Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.

Authors:  Federica Sotgia; Francesco Del Galdo; Mathew C Casimiro; Gloria Bonuccelli; Isabelle Mercier; Diana Whitaker-Menezes; Kristin M Daumer; Jie Zhou; Chenguang Wang; Sanjay Katiyar; Huan Xu; Emily Bosco; Andrew A Quong; Bruce Aronow; Agnieszka K Witkiewicz; Carlo Minetti; Philippe G Frank; Sergio A Jimenez; Erik S Knudsen; Richard G Pestell; Michael P Lisanti
Journal:  Am J Pathol       Date:  2009-03       Impact factor: 4.307

Review 9.  Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator.

Authors:  Richard C Scarpulla
Journal:  Ann N Y Acad Sci       Date:  2008-12       Impact factor: 5.691

Review 10.  Cyclin D1, cancer progression, and opportunities in cancer treatment.

Authors:  Shuo Qie; J Alan Diehl
Journal:  J Mol Med (Berl)       Date:  2016-10-02       Impact factor: 4.599
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