Literature DB >> 16863649

Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?

R Dumaine, C Antzelevitch.   

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Year:  2006        PMID： 16863649      PMCID： PMC1989772          DOI： 10.1016/j.yjmcc.2006.06.070

Source DB:  PubMed          Journal:  J Mol Cell Cardiol        ISSN： 0022-2828            Impact factor:   5.000


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  25 in total

1.  HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine.

Authors:  M Roy; R Dumaine; A M Brown
Journal:  Circulation       Date:  1996-08-15       Impact factor: 29.690

Review 2.  Long QT syndrome: reduced repolarization reserve and the genetic link.

Authors:  D M Roden
Journal:  J Intern Med       Date:  2006-01       Impact factor: 8.989

3.  Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.

Authors:  Christian Wolpert; Rainer Schimpf; Carla Giustetto; Charles Antzelevitch; Jonathan Cordeiro; Robert Dumaine; Ramon Brugada; Kui Hong; Urs Bauersfeld; Fiorenzo Gaita; Martin Borggrefe
Journal:  J Cardiovasc Electrophysiol       Date:  2005-01

4.  Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome.

Authors:  Fabrice Extramiana; Charles Antzelevitch
Journal:  Circulation       Date:  2004-11-29       Impact factor: 29.690

5.  Early afterdepolarizationlike activity in patients with class IA induced long QT syndrome and torsades de pointes.

Authors:  T Kurita; T Ohe; W Shimizu; K Suyama; N Aihara; H Takaki; S Kamakura; K Shimomura
Journal:  Pacing Clin Electrophysiol       Date:  1997-03       Impact factor: 1.976

6.  Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome.

Authors:  Mark J McPate; Rona S Duncan; Harry J Witchel; Jules C Hancox
Journal:  J Mol Cell Cardiol       Date:  2006-07-12       Impact factor: 5.000

7.  Congenital short QT syndrome and implantable cardioverter defibrillator treatment: inherent risk for inappropriate shock delivery.

Authors:  Rainer Schimpf; Christian Wolpert; Francesca Bianchi; Carla Giustetto; Florenzo Gaita; Urs Bauersfeld; Martin Borggrefe
Journal:  J Cardiovasc Electrophysiol       Date:  2003-12

8.  Sudden death associated with short-QT syndrome linked to mutations in HERG.

Authors:  Ramon Brugada; Kui Hong; Robert Dumaine; Jonathan Cordeiro; Fiorenzo Gaita; Martin Borggrefe; Teresa M Menendez; Josep Brugada; Guido D Pollevick; Christian Wolpert; Elena Burashnikov; Kiyotaka Matsuo; Yue Sheng Wu; Alejandra Guerchicoff; Francesca Bianchi; Carla Giustetto; Rainer Schimpf; Pedro Brugada; Charles Antzelevitch
Journal:  Circulation       Date:  2003-12-15       Impact factor: 29.690

9.  Blockade of HERG and Kv1.5 by ketoconazole.

Authors:  R Dumaine; M L Roy; A M Brown
Journal:  J Pharmacol Exp Ther       Date:  1998-08       Impact factor: 4.030

10.  A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel.

Authors:  M C Sanguinetti; C Jiang; M E Curran; M T Keating
Journal:  Cell       Date:  1995-04-21       Impact factor: 41.582
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  3 in total

Review 1.  Cardiac Delayed Rectifier Potassium Channels in Health and Disease.

Authors:  Lei Chen; Kevin J Sampson; Robert S Kass
Journal:  Card Electrophysiol Clin       Date:  2016-04-01

2.  Computational Analysis of the Mode of Action of Disopyramide and Quinidine on hERG-Linked Short QT Syndrome in Human Ventricles.

Authors:  Dominic G Whittaker; Haibo Ni; Alan P Benson; Jules C Hancox; Henggui Zhang
Journal:  Front Physiol       Date:  2017-10-04       Impact factor: 4.566

3.  In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome.

Authors:  Dominic G Whittaker; Jules C Hancox; Henggui Zhang
Journal:  Front Physiol       Date:  2019-01-11       Impact factor: 4.566
  3 in total

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