Literature DB >> 168628

The nasal secretion and serum antibody response of lambs following vaccination and aerosol challenge with parainfluenza 3 virus.

W D Smith.   

Abstract

The nasal and serum neutralising antibody responses of lambs was compared following vaccination with live or inactivated parainfluenza 3 (PI 3) virus by either intramuscular (IM) or intranasal (IN) routes. Nasal antibody was only detected following inoculation of live virus IN or inactivated virus in Freund's complete adjuvant (FCA) IM. Immunity to aerosol challenge, as assessed by viral shedding from the nose, was conferred by (1) live virus administered by either route, (2) two IM inoculations of inactivated virus in FCA, and (3) one IM injection of inactivated virus in FCA followed by IN instillation of inactivated virus.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 168628

Source DB:  PubMed          Journal:  Res Vet Sci        ISSN： 0034-5288            Impact factor:   2.534


  4 in total

1.  Maternal immunoglobulins and parainfluenza 3 virus inhibitors in the nasal and lachrymal secretions and serum of newborn lambs.

Authors:  W D Smith; P W Wells; C Burrells; A M Dawson
Journal:  Clin Exp Immunol       Date:  1976-03       Impact factor: 4.330

2.  Immunoglobulins, antibodies and inhibitors of parainfluenza 3 virus in respiratory secretions of sheep.

Authors:  W D Smith; P W Wells; C Burrells; A M Dawson
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

3.  Protection from parainfluenza-3 virus and persistence of infectious bovine rhinotracheitis virus in sheep vaccinated with a modified live IBR-PI-3 vaccine.

Authors:  H D Lehmkuhl; R C Cutlip
Journal:  Can J Comp Med       Date:  1985-01

4.  The assessment in sheep of an inactivated vaccine of parainfluenza 3 virus incorporating double stranded RNA (BRL 5907) as adjuvant.

Authors:  P W Wells; J M Sharp; C Burrells; B Rushton; W D Smith
Journal:  J Hyg (Lond)       Date:  1976-10
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.