Literature DB >> 1686172

X-linked immunodeficiencies: clues to genes involved in T- and B-cell differentiation.

G de Saint Basile1, A Fischer.   

Abstract

There are five major human X-linked immunodeficiencies, each with a characteristic impairment of T-and/or B-cell differentiation. The molecular bases of these diseases remain unknown but, as Geneviève de Saint Basile and Alain Fischer report, major steps towards that goal have been taken: the location of the defective genes has been precisely defined and the cell lineages and stages of differentiation in which the genes are expressed have been partly identified.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1686172     DOI： 10.1016/0167-5699(91)90019-p

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  4 in total

1.  Bone marrow cells in X-linked agammaglobulinemia express pre-B-specific genes (lambda-like and V pre-B) and present immunoglobulin V-D-J gene usage strongly biased to a fetal-like repertoire.

Authors:  M Milili; F Le Deist; G de Saint-Basile; A Fischer; M Fougereau; C Schiff
Journal:  J Clin Invest       Date:  1993-04       Impact factor: 14.808

Review 2.  Cellular and molecular basis of immunodeficiencies: their consequences for the development and induction of the immune response.

Authors:  J Sterzl
Journal:  Folia Microbiol (Praha)       Date:  1998       Impact factor: 2.099

3.  A putative human equivalent of the murine Xlr (X-linked, lymphocyte-regulated) protein.

Authors:  B Allenet; D Escalier; H J Garchon
Journal:  Mamm Genome       Date:  1995-09       Impact factor: 2.957

4.  Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study.

Authors:  Daniele Moratto; Silvia Giliani; Carmem Bonfim; Evelina Mazzolari; Alain Fischer; Hans D Ochs; Andrew J Cant; Adrian J Thrasher; Morton J Cowan; Michael H Albert; Trudy Small; Sung-Yun Pai; Elie Haddad; Antonella Lisa; Sophie Hambleton; Mary Slatter; Marina Cavazzana-Calvo; Nizar Mahlaoui; Capucine Picard; Troy R Torgerson; Lauri Burroughs; Adriana Koliski; Jose Zanis Neto; Fulvio Porta; Waseem Qasim; Paul Veys; Kristina Kavanau; Manfred Hönig; Ansgar Schulz; Wilhelm Friedrich; Luigi D Notarangelo
Journal:  Blood       Date:  2011-06-09       Impact factor: 22.113
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.