OBJECT: Intramedullary cavernous malformations (CMs) account for approximately 5% of all intraspinal lesions. The purpose of this study was to define the spectrum of presentation for spinal intramedullary CMs and the results of microsurgery for these benign but clinically progressive lesions. METHODS: Retrospective chart review was performed in 26 patients with histologically diagnosed CMs. All patients had undergone preoperative magnetic resonance (MR) imaging studies. All patients were treated with a laminectomy and microsurgical resection of the malformation. CONCLUSIONS: The MR imaging findings are diagnostic for intramedullary CMs; these lesions abut a pial surface and have a characteristic imaging pattern. Spinal intramedullary CMs present with either an acute onset of neurological compromise or a slowly progressive neurological decline. Acute neurological decline occurs secondary to hemorrhage inside the spinal cord. Chronic progressive myelopathy occurs due to microhemorrhages and resulting gliotic reaction to blood products. Surgery and total removal of the lesion tends to halt progression of symptoms.
OBJECT: Intramedullary cavernous malformations (CMs) account for approximately 5% of all intraspinal lesions. The purpose of this study was to define the spectrum of presentation for spinal intramedullary CMs and the results of microsurgery for these benign but clinically progressive lesions. METHODS: Retrospective chart review was performed in 26 patients with histologically diagnosed CMs. All patients had undergone preoperative magnetic resonance (MR) imaging studies. All patients were treated with a laminectomy and microsurgical resection of the malformation. CONCLUSIONS: The MR imaging findings are diagnostic for intramedullary CMs; these lesions abut a pial surface and have a characteristic imaging pattern. Spinal intramedullary CMs present with either an acute onset of neurological compromise or a slowly progressive neurological decline. Acute neurological decline occurs secondary to hemorrhage inside the spinal cord. Chronic progressive myelopathy occurs due to microhemorrhages and resulting gliotic reaction to blood products. Surgery and total removal of the lesion tends to halt progression of symptoms.
Authors: Oliver Bozinov; Jan-Karl Burkhardt; Christoph M Woernle; Vincent Hagel; Nils H Ulrich; Niklaus Krayenbühl; Helmut Bertalanffy Journal: Neurosurg Rev Date: 2011-11-12 Impact factor: 3.042
Authors: Heather Kate Moriarty; Roisin O Cearbhaill; Peter D Moriarty; Emma Stanley; Leo P Lawler; Eoin C Kavanagh Journal: Br J Radiol Date: 2018-11-27 Impact factor: 3.039
Authors: Sauson Soldozy; Parantap Patel; Mazin Elsarrag; Pedro Norat; Daniel M Raper; Jennifer D Sokolowski; Kaan Yağmurlu; Min S Park; Petr Tvrdik; M Yashar S Kalani Journal: Spinal Cord Date: 2019-07-29 Impact factor: 2.772
Authors: Erwin M J Cornips; Pauline A C P Vinken; Mariel Ter Laak-Poort; Emile A M Beuls; Jacobine Weber; Johannes S H Vles Journal: Childs Nerv Syst Date: 2009-10-29 Impact factor: 1.475