Literature DB >> 16859064

The effect of folic acid supplementation in beta-thalassemia major: a randomized placebo-controlled clinical trial.

Fereidoon Mojtahedzadeh1, Mehrnoush Kosaryan, Mohammad-Reza Mahdavi, Jafar Akbari.   

Abstract

Folic acid is a coenzyme for many important biochemical reactions including synthesis of purines, pyrimidines, and nucleoproteins. The recommended daily allowance of folic acid is 65 - 200 microg/day for infants and children. The recommended dose for deficiency states is 1000 microg/day; the effects of excess amounts of folic acid are unknown. The role of folic acid in preventing progression of arteriosclerosis is rather a new issue. Thrombotic events related to slightly elevated levels of homocystein in adults may be decreased by daily consumption of 1 mg of folic acid together with 5 - 100 mg of pyridoxine.

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Year:  2006        PMID： 16859064

Source DB:  PubMed          Journal:  Arch Iran Med        ISSN： 1029-2977            Impact factor:   1.354


  6 in total

1.  Nutrition in Thalassemia: A Systematic Review of Deficiency, Relations to Morbidity, and Supplementation Recommendations.

Authors:  Elijah K Goldberg; Ashutosh Lal; Ellen B Fung
Journal:  J Pediatr Hematol Oncol       Date:  2022-01-01       Impact factor: 1.289

Review 2.  Folate supplementation in people with sickle cell disease.

Authors:  Ruchita Dixit; Sowmya Nettem; Simerjit S Madan; Htoo Htoo Kyaw Soe; Adinegara B L Abas; Leah D Vance; Patrick J Stover
Journal:  Cochrane Database Syst Rev       Date:  2016-02-16

Review 3.  Endocrine and bone complications in β-thalassemia intermedia: current understanding and treatment.

Authors:  Adlette Inati; MohammadHassan A Noureldine; Anthony Mansour; Hussein A Abbas
Journal:  Biomed Res Int       Date:  2015-03-05       Impact factor: 3.411

4.  Folate supplementation in transfusion-dependent thalassemia: Do we really need such high doses?

Authors:  Gaurav Tripathi; Manas Kalra; Amita Mahajan
Journal:  Indian J Med Paediatr Oncol       Date:  2016 Oct-Dec

Review 5.  Folate supplementation in people with sickle cell disease.

Authors:  Ruchita Dixit; Sowmya Nettem; Simerjit S Madan; Htoo Htoo Kyaw Soe; Adinegara Bl Abas; Leah D Vance; Patrick J Stover
Journal:  Cochrane Database Syst Rev       Date:  2018-03-16

6.  Treatment Status of Patients with B-Thalassemia Major in Northern Iran: Thalassemia Registry System.

Authors:  Mehrnoush Kosaryan; Hossein Karami; Hadi Darvishi-Khezri; Rosetta Akbarzadeh; Aily Aliasgharian; Khadijeh Bromand
Journal:  Iran J Public Health       Date:  2019-07       Impact factor: 1.429
  6 in total

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