Literature DB >> 16857957

The nine lives of ACAT inhibitors.

Robert V Farese.   

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Year:  2006        PMID： 16857957     DOI： 10.1161/01.ATV.0000227511.35456.90

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


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  9 in total

1.  Avasimibe encapsulated in human serum albumin blocks cholesterol esterification for selective cancer treatment.

Authors:  Steve Seung-Young Lee; Junjie Li; Jien Nee Tai; Timothy L Ratliff; Kinam Park; Ji-Xin Cheng
Journal:  ACS Nano       Date:  2015-02-16       Impact factor: 15.881

Review 2.  ACAT inhibition and amyloid beta reduction.

Authors:  Raja Bhattacharyya; Dora M Kovacs
Journal:  Biochim Biophys Acta       Date:  2010-04-14

3.  Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.

Authors:  Adam M Lopez; Kenneth S Posey; Stephen D Turley
Journal:  Biochem Biophys Res Commun       Date:  2014-10-18       Impact factor: 3.575

4.  Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid rafts.

Authors:  Raja Bhattacharyya; Cory Barren; Dora M Kovacs
Journal:  J Neurosci       Date:  2013-07-03       Impact factor: 6.167

5.  Loss of apoptosis regulator through modulating IAP expression (ARIA) protects blood vessels from atherosclerosis.

Authors:  Kiyonari Matsuo; Yoshiki Akakabe; Youhei Kitamura; Yoshiaki Shimoda; Kazunori Ono; Tomomi Ueyama; Satoaki Matoba; Hiroyuki Yamada; Kinta Hatakeyama; Yujiro Asada; Noriaki Emoto; Koji Ikeda
Journal:  J Biol Chem       Date:  2014-12-22       Impact factor: 5.157

6.  PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.

Authors:  Adam M Lopez; Jen-Chieh Chuang; Kenneth S Posey; Taichi Ohshiro; Hiroshi Tomoda; Lawrence L Rudel; Stephen D Turley
Journal:  J Pharmacol Exp Ther       Date:  2015-08-17       Impact factor: 4.030

7.  Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells.

Authors:  Aicha Saadane; Natalia Mast; Tung Dao; Baseer Ahmad; Irina A Pikuleva
Journal:  J Biol Chem       Date:  2016-08-11       Impact factor: 5.157

Review 8.  Acyl-Coenzyme A: Cholesterol Acyltransferase (ACAT) in Cholesterol Metabolism: From Its Discovery to Clinical Trials and the Genomics Era.

Authors:  Qimin Hai; Jonathan D Smith
Journal:  Metabolites       Date:  2021-08-14

9.  Cholesterol homeostasis: a key to prevent or slow down neurodegeneration.

Authors:  Laura Anchisi; Sandra Dessì; Alessandra Pani; Antonella Mandas
Journal:  Front Physiol       Date:  2013-01-04       Impact factor: 4.566
  9 in total

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