Literature DB >> 16857582

DNA replication: keep moving and don't mind the gap.

Lance D Langston1, Mike O'Donnell.   

Abstract

As the replication fork progresses, synthesis of the discontinuous lagging strand requires frequent priming and cycling of the lagging strand polymerase to the new primers. It appears that this mechanism also permits bypass of template lesions on both strands, leaving the damage behind in a single-strand gap and precluding fork stalling or collapse.

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Year:  2006        PMID: 16857582     DOI: 10.1016/j.molcel.2006.05.034

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  36 in total

Review 1.  Folded DNA in action: hairpin formation and biological functions in prokaryotes.

Authors:  David Bikard; Céline Loot; Zeynep Baharoglu; Didier Mazel
Journal:  Microbiol Mol Biol Rev       Date:  2010-12       Impact factor: 11.056

2.  Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli.

Authors:  Ashok S Bhagwat; Weilong Hao; Jesse P Townes; Heewook Lee; Haixu Tang; Patricia L Foster
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-02       Impact factor: 11.205

3.  Simulating the temporal modulation of inducible DNA damage response in Escherichia coli.

Authors:  Ming Ni; Si-Yuan Wang; Ji-Kun Li; Qi Ouyang
Journal:  Biophys J       Date:  2007-04-13       Impact factor: 4.033

4.  A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp.

Authors:  Asako Furukohri; Myron F Goodman; Hisaji Maki
Journal:  J Biol Chem       Date:  2008-02-28       Impact factor: 5.157

5.  A novel mechanistic spectrum underlies glaucoma-associated chromosome 6p25 copy number variation.

Authors:  Bhaskar Chanda; Mika Asai-Coakwell; Ming Ye; Andrew J Mungall; Margaret Barrow; William B Dobyns; Hourinaz Behesti; Jane C Sowden; Nigel P Carter; Michael A Walter; Ordan J Lehmann
Journal:  Hum Mol Genet       Date:  2008-08-11       Impact factor: 6.150

6.  Repriming of DNA synthesis at stalled replication forks by human PrimPol.

Authors:  Silvana Mourón; Sara Rodriguez-Acebes; María I Martínez-Jiménez; Sara García-Gómez; Sandra Chocrón; Luis Blanco; Juan Méndez
Journal:  Nat Struct Mol Biol       Date:  2013-11-17       Impact factor: 15.369

7.  Presynaptic filament dynamics in homologous recombination and DNA repair.

Authors:  Jie Liu; Kirk T Ehmsen; Wolf-Dietrich Heyer; Scott W Morrical
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-06       Impact factor: 8.250

8.  Virion-associated, host-derived DHX9/RNA helicase A enhances the processivity of HIV-1 reverse transcriptase on genomic RNA.

Authors:  Samantha Brady; Gatikrushna Singh; Cheryl Bolinger; Zhenwei Song; Ioana Boeras; Kexin Weng; Bria Trent; William Clay Brown; Kamalendra Singh; Kathleen Boris-Lawrie; Xiao Heng
Journal:  J Biol Chem       Date:  2019-06-07       Impact factor: 5.157

9.  Continued primer synthesis at stalled replication forks contributes to checkpoint activation.

Authors:  Christopher Van; Shan Yan; W Matthew Michael; Shou Waga; Karlene A Cimprich
Journal:  J Cell Biol       Date:  2010-04-12       Impact factor: 10.539

10.  Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.

Authors:  Sushil Chandani; Christopher Jacobs; Edward L Loechler
Journal:  J Nucleic Acids       Date:  2010-09-16
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