Literature DB >> 16857581

H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation.

Hayla K Sluss1, Roger J Davis.   

Abstract

The mechanism of apoptotic signaling by JNK is incompletely understood. In the July 7 issue of Molecular Cell, Lu et al. (2006) report that JNK phosphorylation of H2AX at a noncanonical site is required for caspase-induced DNA fragmentation.

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Year:  2006        PMID： 16857581     DOI： 10.1016/j.molcel.2006.07.001

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  25 in total

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