| Literature DB >> 16857579 |
Abstract
Targeting proteins for irreversible degradation must be under tight control and is often regulated at the level of substrate-receptor binding. But does a protein really need to be marked twice with two different modifications, first phosphorylation and then isomerization, to bind its receptor, as van Drogen et al. (2006) show for cyclin E?Entities:
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Year: 2006 PMID： 16857579 DOI： 10.1016/j.molcel.2006.07.002
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970