Literature DB >> 16855881

No debridement is necessary for symptomatic or infected acute necrotizing pancreatitis: delayed, mini-retroperitoneal drainage for acute necrotizing pancreatitis without debridement and irrigation.

Yu-Chung Chang1, Hong-Min Tsai, Xi-Zhang Lin, Chia-Hao Chang, Jen Pin Chuang.   

Abstract

We sought to determine if necrosectomy can be omitted for complicated acute necrotizing pancreatitis (ANP). Since 1996, we prospectively performed retroperitoneal drainage by introducing a sump drain to the pancreatic head area via a small left flank incision without debridement and irrigation on 19 consecutive complicated ANP patients. We purposely delayed surgery until liquefaction of retroperitoneal tissue reached the left flank. Our patients had a mean Ranson's and APACHE II score of 5.9 (range, 4-8) and 20.1(range, 4-45), respectively. Sixteen available CT showed retroperitoneal liquefaction after 21.3 days (range, 14-26). Operations were delayed for 4.7 weeks (range, 1.3-9.0). No patient succumbed during this period. The indications were infected necrosis in 16 and severe abdominal pain/food intolerance in 3 patients. Average skin incision was 4.0 cm (range, 3-9). Fungi or bacteria were cultured in 15 patients (80.0%). The recovery courses were surprisingly uneventful. Oral intake began within 2.4 days (range, 1-5) and mean hospital stay (16 survivals) was 23.2 days (range, 4-120) after operation. Drains were completely removed 120.6 days (range, 60-250) later from these outpatients. One gastric perforation and one minor duodenal leak were the only procedure-related complications (10.5%). Three patients died (15.8%), although one had a healed ANP. In conclusion, this delay-until-liquefaction strategy without necrosectomy is an easy and effective treatment method.

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Year:  2006        PMID: 16855881     DOI: 10.1007/s10620-006-9112-6

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  46 in total

1.  Retroperitoneal endoscopic debridement for infected peripancreatic necrosis.

Authors:  H Seifert; T Wehrmann; T Schmitt; S Zeuzem; W F Caspary
Journal:  Lancet       Date:  2000-08-19       Impact factor: 79.321

2.  Percutaneous necrosectomy and sinus tract endoscopy in the management of infected pancreatic necrosis: an initial experience.

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Journal:  Ann Surg       Date:  2000-08       Impact factor: 12.969

3.  [Percutaneous drainage of infected pancreatic necrosis: an alternative to surgery].

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Journal:  Chirurgie       Date:  1999-02

4.  Does mortality occur early or late in acute pancreatitis?

Authors:  M Mutinga; A Rosenbluth; S M Tenner; R R Odze; G T Sica; P A Banks
Journal:  Int J Pancreatol       Date:  2000-10

Review 5.  The role of surgery in the management of acute pancreatitis.

Authors:  J H Ranson
Journal:  Ann Surg       Date:  1990-04       Impact factor: 12.969

6.  Percutaneous CT-guided catheter drainage of infected acute necrotizing pancreatitis: techniques and results.

Authors:  P C Freeny; E Hauptmann; S J Althaus; L W Traverso; M Sinanan
Journal:  AJR Am J Roentgenol       Date:  1998-04       Impact factor: 3.959

7.  Techniques and complications of open packing of infected pancreatic necrosis.

Authors:  R Orlando; J P Welch; C M Akbari; G P Bloom; W P Macaulay
Journal:  Surg Gynecol Obstet       Date:  1993-07

8.  Direct retroperitoneal approach to necrosis in severe acute pancreatitis.

Authors:  P L Fagniez; N Rotman; M Kracht
Journal:  Br J Surg       Date:  1989-03       Impact factor: 6.939

9.  Failure of percutaneous drainage of pancreatic abscesses complicating severe acute pancreatitis.

Authors:  N Rotman; D Mathieu; M C Anglade; P L Fagniez
Journal:  Surg Gynecol Obstet       Date:  1992-02

10.  Pancreatic debridement in acute necrotizing pancreatitis: an obsolete procedure?

Authors:  C Smadja; H Bismuth
Journal:  Br J Surg       Date:  1986-05       Impact factor: 6.939

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  12 in total

1.  Laparotomy versus retroperitoneal laparoscopy in debridement and drainage of retroperitoneal infected necrosis in severe acute pancreatitis.

Authors:  Yuliang Tu; Huabo Jiao; Xianglong Tan; Liyuan Sun; Wenzhi Zhang
Journal:  Surg Endosc       Date:  2013-06-21       Impact factor: 4.584

Review 2.  Management of pancreatic fluid collections: A comprehensive review of the literature.

Authors:  Amy Tyberg; Kunal Karia; Moamen Gabr; Amit Desai; Rushabh Doshi; Monica Gaidhane; Reem Z Sharaiha; Michel Kahaleh
Journal:  World J Gastroenterol       Date:  2016-02-21       Impact factor: 5.742

3.  Management of infected pancreatic necrosis using retroperitoneal necrosectomy with flexible endoscope: 10 years of experience.

Authors:  Gregorio Castellanos; Antonio Piñero; Laura A Doig; Andrés Serrano; Matilde Fuster; Vicente Bixquert
Journal:  Surg Endosc       Date:  2012-07-18       Impact factor: 4.584

Review 4.  Minimally invasive treatment of pancreatic necrosis.

Authors:  Brian Bello; Jeffrey B Matthews
Journal:  World J Gastroenterol       Date:  2012-12-14       Impact factor: 5.742

5.  Open transgastric debridement and internal drainage of symptomatic non-infected walled-off pancreatic necrosis.

Authors:  Gitonga Munene; Elijah Dixon; Francis Sutherland
Journal:  HPB (Oxford)       Date:  2011-03-02       Impact factor: 3.647

6.  Current status of minimally invasive necrosectomy for post-inflammatory pancreatic necrosis.

Authors:  Benoy Idicula Babu; Ajith Kumar Siriwardena
Journal:  HPB (Oxford)       Date:  2009-03       Impact factor: 3.647

Review 7.  Is necrosectomy obsolete for infected necrotizing pancreatitis? Is a paradigm shift needed?

Authors:  Yu-Chung Chang
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

8.  Focused open necrosectomy in necrotizing pancreatitis.

Authors:  Guntars Pupelis; Vladimir Fokin; Kaspars Zeiza; Haralds Plaudis; Anastasija Suhova; Nadezda Drozdova; Viesturs Boka
Journal:  HPB (Oxford)       Date:  2012-11-22       Impact factor: 3.647

Review 9.  Intervention in necrotizing pancreatitis: an evidence-based review of surgical and percutaneous alternatives.

Authors:  Edward L Bradley; Thomas J Howard; Eric van Sonnenberg; Mehran Fotoohi
Journal:  J Gastrointest Surg       Date:  2008-01-03       Impact factor: 3.452

10.  Minimally invasive retroperitoneal necrosectomy in management of acute necrotizing pancreatitis.

Authors:  Audrius Sileikis; Virgilijus Beiša; Augustas Beiša; Artūras Samuilis; Mindaugas Serpytis; Kęstutis Strupas
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2012-10-08       Impact factor: 1.195

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